Effects of highly purified urinary FSH and human menopausal FSH on uterine myoelectrical dynamics

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dc.authoridTağluk, M. Emin/0000-0001-7789-6376
dc.authoridAYDIN, Nasuhi/0000-0003-3145-2432
dc.authorwosidTağluk, M. Emin/ABH-1005-2020
dc.authorwosidINCI YILDIRIM, AYŞE/AAL-1847-2020
dc.authorwosidAydin, Nasuhi E/B-6536-2012
dc.authorwosidAYDIN, Nasuhi Engin/L-1607-2019
dc.authorwosidAYDIN, Nasuhi/O-9043-2016
dc.contributor.authorHascalik, Seyma
dc.contributor.authorCelik, Onder
dc.contributor.authorTagluk, M. Emin
dc.contributor.authorYildirim, Ayse
dc.contributor.authorAydin, N. Engin
dc.date.accessioned2024-08-04T20:32:22Z
dc.date.available2024-08-04T20:32:22Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of the study was to investigate the effects of urinary follicle-stimulating hormone (FSH) compounds on the electrical activity of myometrium using signal-processing techniques. Thirty animals were involved in the experiment. After two successive normal estrous cycles, 15 of these animals were put into three equal subgroups. Group 1 was the control; animals were given solvent. Groups 2 and 3 were treated with Urofollitropin and Menotropin, respectively. The other 15 animals were ovariectomized and subjected to the same protocol. Their uterine myoelectrical signals were recorded over a period of at least 3 min at a sampling frequency of 500 Hz, and analyzed through software assisted signal processing. The results show the power and some characteristic spectral components of myoelectrical signal were differentially reduced with the administration of highly purified urinary FSH and human menopausal FSH but significant differences were not detected between their histology. In conclusion, uterine myoelectrical signals change with administration of urinary FSH preparations. Human menopausal FSH and more precisely highly purified FSH suppress the spectral components and modify the power of the myoelectrical signals which provides uterine quiescence.en_US
dc.identifier.doi10.1093/molehr/gap076
dc.identifier.endpage206en_US
dc.identifier.issn1460-2407
dc.identifier.issue3en_US
dc.identifier.pmid19720661en_US
dc.identifier.scopus2-s2.0-77950206777en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage200en_US
dc.identifier.urihttps://doi.org/10.1093/molehr/gap076
dc.identifier.urihttps://hdl.handle.net/11616/95011
dc.identifier.volume16en_US
dc.identifier.wosWOS:000274342700007en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherOxford Univ Pressen_US
dc.relation.ispartofMolecular Human Reproductionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectmyoelectrical signal highly purified urinary FSHen_US
dc.subjecthuman menopausal FSHen_US
dc.subjectendometriumen_US
dc.titleEffects of highly purified urinary FSH and human menopausal FSH on uterine myoelectrical dynamicsen_US
dc.typeArticleen_US

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