Chronic effects of fluoride in Tuj sheep on serum levels of total protein, albumin, uric acid, and nitric oxide and activities of lactate dehydrogenase and leucine aminopeptidase

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dc.authorwosidCenesiz, Sena/HJJ-1574-2023
dc.contributor.authorCenesiz, S
dc.contributor.authorOzcan, A
dc.contributor.authorKaya, N
dc.contributor.authorBaysu, N
dc.contributor.authorKarabulut, AB
dc.date.accessioned2024-08-04T20:13:49Z
dc.date.available2024-08-04T20:13:49Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractTwenty healthy yearling Tuj ewe-lambs with a mean body weight of 31 2 kg were divided into two equal groups. Each group of ten sheep was provided with hay and water ad libitum throughout the study. The water for the control group contained 0.49 mg F/L, whereas the water for the experimental group contained 13.8 mg F/L, equivalent for the latter group to an intake of ca. 1.8 mg F/kg bw/day. By the 12(th) week the urinary fluoride concentration in the experimental group had increased from 0.9 ppm at the start to 1.78 ppm, and by the 24(th) week it reached 8 ppm, at which point various serum determinations were made and the study was terminated. In the experimental vs. the control groups the results were as follows: total protein 7.41 +/- 0.03 vs. 7.67 +/- 0.07 g/dL (p<0.01), albumin 3.97 +/- 0.36 vs. 4.72 +/- 0.28 g/dL, nitric oxide 49.90 +/- 3.1 vs. 35.75 +/- 2.7 mu mol/L (p < 0.01), uric acid 0.49 +/- 0.03 vs. 0.29 +/- 0.02 mg/dL (p < 0.001), lactate dehydrogenase (LDH) 676.7 +/- 21 vs. 518 +/- 35 U/L (p < 0.01), and leucine aminopeptidase (LAP) 7.28 +/- 0.5 vs. 6.18 +/- 0.53 U/L. Changes in the albumin level and the LAP activity were not statistically significant. During and at the end of the study the urine fluoride concentration of the control group was unchanged.en_US
dc.identifier.endpage56en_US
dc.identifier.issn0015-4725
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-16444367154en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage52en_US
dc.identifier.urihttps://hdl.handle.net/11616/93870
dc.identifier.volume38en_US
dc.identifier.wosWOS:000227899300008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherInt Soc Fluoride Researchen_US
dc.relation.ispartofFluorideen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectalbuminen_US
dc.subjectlactate dehydrogenase (LDH)en_US
dc.subjectleucine aminopeptidase (LAP)en_US
dc.subjectnitric oxideen_US
dc.subjectproteinen_US
dc.subjectsheep serumen_US
dc.subjectTuj sheepen_US
dc.subjecturic aciden_US
dc.titleChronic effects of fluoride in Tuj sheep on serum levels of total protein, albumin, uric acid, and nitric oxide and activities of lactate dehydrogenase and leucine aminopeptidaseen_US
dc.typeArticleen_US

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