Synthesis and characterization of biodegradable pHEMA-starch composites for immobilization of L-asparaginase

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dc.authoridUlu, Ahmet/0000-0002-4447-6233
dc.authoridAteş, Burhan/0000-0001-6080-229X
dc.authoridKoytepe, Suleyman/0000-0002-4788-278X
dc.authorwosidUlu, Ahmet/L-5180-2016
dc.authorwosidKöytepe, Süleyman/AAA-4168-2021
dc.authorwosidAteş, Burhan/AAA-3730-2021
dc.contributor.authorUlu, Ahmet
dc.contributor.authorKoytepe, Suleyman
dc.contributor.authorAtes, Burhan
dc.date.accessioned2024-08-04T20:41:22Z
dc.date.available2024-08-04T20:41:22Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this paper, poly (2-hydroxyethyl methacrylate) (pHEMA) and poly (2-hydroxyethyl methacrylate)-starch (pHEMA-S) composites were prepared from 2-hydroxyethyl methacrylate and different ratio starch. The pHEMA-S showed high thermal stability and biodegradability. The biodegradability of pHEMA-S composites was in the range of 14-22 % for 4 weeks depending on the starch ratio of pHEMA-S. Then, L-ASNase was immobilized onto pHEMA-S composites. The immobilized L-ASNase was investigated with optimum temperature, pH and kinetic parameters. Immobilization improved the pH stability and thermal stability of the enzyme. The K-m values were 1.58 and 0.56 mM for free and immobilized enzyme, respectively.en_US
dc.description.sponsorshipInonu University Scientific Research Projects Unit [BAP 2013/37]en_US
dc.description.sponsorshipThis work was partially supported by The Inonu University Scientific Research Projects Unit (Grant No. BAP 2013/37).en_US
dc.identifier.doi10.1007/s00289-015-1583-1
dc.identifier.endpage1907en_US
dc.identifier.issn0170-0839
dc.identifier.issn1436-2449
dc.identifier.issue7en_US
dc.identifier.scopus2-s2.0-84949518148en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1891en_US
dc.identifier.urihttps://doi.org/10.1007/s00289-015-1583-1
dc.identifier.urihttps://hdl.handle.net/11616/97082
dc.identifier.volume73en_US
dc.identifier.wosWOS:000378781000007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofPolymer Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectL-asparaginaseen_US
dc.subjectpHEMAen_US
dc.subjectpHEMA-starch compositesen_US
dc.subjectImmobilizationen_US
dc.titleSynthesis and characterization of biodegradable pHEMA-starch composites for immobilization of L-asparaginaseen_US
dc.typeArticleen_US

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