Trace element status (Se, Zn, Cu) in heart failure

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dc.authorscopusid6701614367
dc.authorscopusid57535532500
dc.authorscopusid6506553303
dc.authorscopusid8832688300
dc.authorscopusid56265702500
dc.authorscopusid6701745769
dc.authorscopusid6603696319
dc.contributor.authorKoşar F.
dc.contributor.authorŞahin I.
dc.contributor.authorTaşkapan Ç.
dc.contributor.authorKüçükbay Z.
dc.contributor.authorGüllü H.
dc.contributor.authorTaşkapan H.
dc.contributor.authorÇehreli Ş.
dc.date.accessioned2024-08-04T20:02:04Z
dc.date.available2024-08-04T20:02:04Z
dc.date.issued2006
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: It has been speculated that trace elements may play a role in the pathogenesis of heart failure. In the present study, we aimed to assess serum concentrations of selenium (Se), zinc (Zn) and copper (Cu) in patients with heart failure (HF) and to compare idiopathic dilated cardiomyopathy (IDCM) and ischemic cardiomyopathy (ICM) patients with healthy controls. Methods: This study population included 54 HF patients (26 IDCM patients and 28 ICM patients) and 30 healthy subjects. Serum levels of selenium, zinc, and copper were assessed by atomic absorption spectrophotometry method. Results: Serum concentrations of Se and Zn in HF patients were significantly lower than in healthy controls (p=0.000 and p<0.01, respectively). However, serum Cu concentrations in these patients were significantly higher than in controls (p=0.000). There were no significant difference in the trace elements status between IDCM and ICM patients (p>0.05 for all parameters). Relationships of the serum trace element concentrations studied with echocardiographic and hemodynamic parameters were not statistically significant. Conclusion: Our study showed that heart failure is associated with lower Se and Zn concentrations, and higher Cu concentration, and serum Se, Zn and Cu element profiles were similar in IDCM and ICM.en_US
dc.identifier.endpage220en_US
dc.identifier.issn1302-8723
dc.identifier.issue3en_US
dc.identifier.pmid16943104en_US
dc.identifier.scopus2-s2.0-33748681935en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage216en_US
dc.identifier.trdizinid64186en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/64186
dc.identifier.urihttps://hdl.handle.net/11616/91398
dc.identifier.volume6en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofAnadolu Kardiyoloji Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIdiopathic dilated cardiomyopathyen_US
dc.subjectCopperen_US
dc.subjectIschemic cardiomyopathyen_US
dc.subjectSeleniumen_US
dc.subjectZincen_US
dc.titleTrace element status (Se, Zn, Cu) in heart failureen_US
dc.typeArticleen_US

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