Comparison of long term clinical outcomes, event free survival rates of patients undergoing enhanced external counterpulsation for coronary artery disease in the United States and Turkey

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dc.authorwosidÇUĞLAN, bilal/AAP-8878-2021
dc.contributor.authorSoran, Ozlem
dc.contributor.authorIkizler, Coskun
dc.contributor.authorSengul, Atilla
dc.contributor.authorCuglan, Bilal
dc.contributor.authorKennard, Elizabeth
dc.contributor.authorKelsey, Sheryl
dc.date.accessioned2024-08-04T20:09:46Z
dc.date.available2024-08-04T20:09:46Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives: This study assessed the long-term efficacy of EECP (Enhanced External Counterpulsation) in Turkish (TR) patients initially and compared these results with the United States (US) in a real world setting. Study design: In this study, 2072 patients were treated and followed in the US and 82 patients were treated and followed in TR. The International EECP Patient Registry Phase I and II was initiated and coordinated at the University of Pittsburgh. The aim of the registry was to assess the outcomes of clinical trials in a real world setting. Another unique feature of this study was to enroll patients not only from university hospitals but also from private hospitals, educational hospitals, and treatment centers. Results:TR patients had less diabetes, hypertension, and hyperlipidemia than US patients (p<0.01) TR patients also had a higher proportion of diastolic augmentation (p<0.001). Both groups showed a significant reduction in the severity of angina after a 35h EECP course (p<0.001). Major Adverse Cardiac Events (MACE) rate (death, coronary artery bypass graft, percutaneous coronary intervention, myocardial infarction) was low in both groups during treatment (2.5% vs. 2.7%). At 1 year follow up, 84% of TR and 76% of US patients had maintained the improvement of angina. Conclusion: Patients presenting for EECP treatment from TR had different baseline profiles from US patients. However, despite the high risk baseline characteristics, both cohorts achieved similar reduction in angina. In the long term follow-up, the MACE rate was low and the improvement after EECP was sustained in most of the patients.en_US
dc.identifier.doi10.5543/tkda.2012.59144
dc.identifier.endpage330en_US
dc.identifier.issn1016-5169
dc.identifier.issue4en_US
dc.identifier.pmid22951848en_US
dc.identifier.scopus2-s2.0-84882768537en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage323en_US
dc.identifier.trdizinid143872en_US
dc.identifier.urihttps://doi.org/10.5543/tkda.2012.59144
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/143872
dc.identifier.urihttps://hdl.handle.net/11616/92411
dc.identifier.volume40en_US
dc.identifier.wosWOS:000421820200005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Soc Cardiologyen_US
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivi-Archives of The Turkish Society of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAgeden_US
dc.subjectangina pectoris/mortality/therapyen_US
dc.subjectcoronary artery disease/epidemiologyen_US
dc.subjectcounterpulsation/methodsen_US
dc.subjectenhanced external counterpulsationen_US
dc.subjectfollow-up studiesen_US
dc.subjectheart failure/epidemiologyen_US
dc.subjectregistriesen_US
dc.subjecttreatment outcomeen_US
dc.subjectTurkey/epidemiologyen_US
dc.titleComparison of long term clinical outcomes, event free survival rates of patients undergoing enhanced external counterpulsation for coronary artery disease in the United States and Turkeyen_US
dc.typeArticleen_US

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