Subcutaneous sarcoidosis masquerading as a mass

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dc.contributor.authorAtila, Aysenur
dc.contributor.authorErmis, Hilal
dc.contributor.authorYolbas, Servet
dc.contributor.authorAlan, Saadet
dc.date.accessioned2026-04-04T13:33:01Z
dc.date.available2026-04-04T13:33:01Z
dc.date.issued2025
dc.departmentİnönü Üniversitesi
dc.description.abstractSarcoidosis is a multisystem granulomatous disease of unknown cause. The skin and lungs are the most commonly affected organs. While classic lesions of cutaneous sarcoidosis include a wide range of dermatological presentations, mass involvement is uncommon. A 43-year-old male presented to the orthopedic clinic with a growing mass on the right hand and wrist. A trucut biopsy of the lesion revealed granulomatous inflammation. However, as the mass enlarged and caused functional loss in the index finger, amputation of the finger was performed due to suspicion of malignancy, particularly a desmoid tumor. Magnetic resonance imaging demonstrated a solid, infiltrative mass with a diffuse pattern extending from the second finger to the wrist. Histopathological examination of the amputated tissue showed non-caseating granulomatous inflammation, negative for acid-fast bacilli, and no evidence of malignancy. The patient was subsequently referred to our clinic and diagnosed with sarcoidosis involving multiple organs. As local progression continued despite methylprednisolone therapy, a second surgical excision was performed, and second-line immunosuppressive therapy was initiated to control the disease. Mass formation is not a typical cutaneous manifestation of sarcoidosis. This case, featuring a suspected malignancy presenting as a hard mass in the right hand and wrist that led to amputation, demonstrates that a benign condition can progress aggressively enough to cause tissue loss. When atypical presentations occur in benign conditions like sarcoidosis, a multidisciplinary and comprehensive approach is essential to guide treatment decisions before undertaking invasive procedures.
dc.identifier.doi10.14744/ejp.2024.1201
dc.identifier.endpage128
dc.identifier.issn2148-3620
dc.identifier.issn2148-5402
dc.identifier.issue2
dc.identifier.scopus2-s2.0-105013287657
dc.identifier.scopusqualityN/A
dc.identifier.startpage124
dc.identifier.trdizinid1345962
dc.identifier.urihttps://doi.org/10.14744/ejp.2024.1201
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1345962
dc.identifier.urihttps://hdl.handle.net/11616/108879
dc.identifier.volume27
dc.identifier.wosWOS:001550614100008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherKare Publ
dc.relation.ispartofEurasian Journal of Pulmonology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250329
dc.subjectAtypical sarcoidosis
dc.subjectsubcutaneous sarcoidosis treatment
dc.titleSubcutaneous sarcoidosis masquerading as a mass
dc.typeArticle

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