Pan-İmmune Inflammatory Index Predicts Increased Epicardial Adipose Tissue in Prediabetics
Küçük Resim Yok
Tarih
2025
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springernature
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objectives Prediabetes is a global health problem due to its adverse effects on glucose metabolism. Prediabetes also triggers many inflammatory mechanisms that can lead to vascular and molecular damage of various systems and organs. Pan-immun inflammatory level (PIV) is a new biomarker that is considered with many ianflammatory conditions. Epicardial adipose tissue (EAT) is also considered an endocrine organ, which has been shown in many studies to be related to inflammation. There are studies showing that inflammatory parameters and epicardial adipose tissue are affected in diabetic patients. However, no such research has been conducted on prediabetic patients. In this study, we aimed to investigate inflammatory parameters and their relationship with epicardial adipose tissue in prediabetic patients. Methods 220 patients with prediabetes and 96 healthy controls were compared in the study regarding laboratory and demographic parameters and echocardiographic evaluations. Results There were significant differences between the groups in various parameters including epicardial adipose tissue (p < 0.001), NLR (p = 0.011); SII (p = 0.003); PIV (p < 0.001), In prediabetic patients, epicardial adipose tissue was correlated with PIV (r: 0.490; p < 0.001), SII (r: 0.248; p < 0.001), and NLR (r: 0.234; p: 0.001). PIV and presence of prediabetes were independent predictors of epicardial adipose tissue. Conclusion In this study, we observed that the presence of prediabetes is associated with EAT thickness. Again, in this patient group, we thought that PIV could be an easily obtainable parameter that could indicate an increase in EAT thickness.
Açıklama
Anahtar Kelimeler
Prediabetes, Pan-immun inflammatory value, Epicardial adipose tissue, Inflammatory markers
Kaynak
Bratislava Medical Journal
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
126
Sayı
3
