Analysis of urine biomarkers for early determination of acute kidney injury in non septic and non asphyxiated critically ill preterm neonates
dc.authorid | TR31161 | en_US |
dc.authorid | TR58684 | en_US |
dc.authorid | TR121762 | en_US |
dc.contributor.author | Karadağ, Ahmet | |
dc.contributor.author | Elmas, Taner | |
dc.contributor.author | Tabel, Yılmaz | |
dc.contributor.author | Özdemir, Ramazan | |
dc.contributor.author | Otlu, Hüsniye Gül | |
dc.date.accessioned | 2017-04-12T12:28:03Z | |
dc.date.available | 2017-04-12T12:28:03Z | |
dc.date.issued | 2016 | |
dc.department | İnönü Üniversitesi | en_US |
dc.description.abstract | Objective: We designed the present study to test the hypothesis that urinary biomarkers might predict acute kidney injury (AKI) development in non-septic and non-asphyxiated critically ill preterm infants. We evaluated urine (u) sistatin–C (uCys-C), kidney injury molecule–1 (uKIM–1) and neutrophil gelatinase associate lipocaline (uNGAL) as markers of AKI. Methods: Sixty-four preterm infants with gestational age between 28 and 32 weeks were included in this study. Biomarkers were measured on day of life (DOL) 1, 3, and 7. Results: uNGAL levels in the AKI group were significantly higher than in no-AKI group on DOL 1, 3 and 7 (p ¼ 0.016, p ¼ 0.007 and p ¼ 0.0014, respectively). Conclusions: uNGAL is sensitive, early, and noninvasive AKI biomarkers, increasing significantly in non-septic and non-asphyxiated critically ill preterm neonates. | en_US |
dc.identifier.citation | Karadağ, A. Elmas, T. Tabel, Y. Özdemir, R. Otlu, H. G. (2016). Analysis of urine biomarkers for early determination of acute kidney injury in non septic and non asphyxiated critically ill preterm neonates. The Journal of Maternal-Fetal & Neonatal Medicine, 30(3), 302–308. | en_US |
dc.identifier.doi | 10.3109/14767058.2016.1171311 | en_US |
dc.identifier.endpage | 308 | en_US |
dc.identifier.issn | 1476-7058 | |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 302 | en_US |
dc.identifier.uri | https://www.tandfonline.com/doi/full/10.3109/14767058.2016.1171311 | |
dc.identifier.uri | https://hdl.handle.net/11616/6652 | |
dc.identifier.volume | 30 | en_US |
dc.language.iso | en | en_US |
dc.publisher | The Journal of Maternal-Fetal & Neonatal Medicine | en_US |
dc.relation.ispartof | The Journal of Maternal-Fetal & Neonatal Medicine | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Acute kidney injury | en_US |
dc.subject | Kidney injury molecule–1 | en_US |
dc.subject | Neutrophil gelatinase associate lipocaline | en_US |
dc.subject | Preterm infants | en_US |
dc.subject | Sistatin–C | en_US |
dc.subject | Urine | en_US |
dc.title | Analysis of urine biomarkers for early determination of acute kidney injury in non septic and non asphyxiated critically ill preterm neonates | en_US |
dc.type | Article | en_US |