Analysis of urine biomarkers for early determination of acute kidney injury in non septic and non asphyxiated critically ill preterm neonates

dc.authoridTR31161en_US
dc.authoridTR58684en_US
dc.authoridTR121762en_US
dc.contributor.authorKaradağ, Ahmet
dc.contributor.authorElmas, Taner
dc.contributor.authorTabel, Yılmaz
dc.contributor.authorÖzdemir, Ramazan
dc.contributor.authorOtlu, Hüsniye Gül
dc.date.accessioned2017-04-12T12:28:03Z
dc.date.available2017-04-12T12:28:03Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: We designed the present study to test the hypothesis that urinary biomarkers might predict acute kidney injury (AKI) development in non-septic and non-asphyxiated critically ill preterm infants. We evaluated urine (u) sistatin–C (uCys-C), kidney injury molecule–1 (uKIM–1) and neutrophil gelatinase associate lipocaline (uNGAL) as markers of AKI. Methods: Sixty-four preterm infants with gestational age between 28 and 32 weeks were included in this study. Biomarkers were measured on day of life (DOL) 1, 3, and 7. Results: uNGAL levels in the AKI group were significantly higher than in no-AKI group on DOL 1, 3 and 7 (p ¼ 0.016, p ¼ 0.007 and p ¼ 0.0014, respectively). Conclusions: uNGAL is sensitive, early, and noninvasive AKI biomarkers, increasing significantly in non-septic and non-asphyxiated critically ill preterm neonates.en_US
dc.identifier.citationKaradağ, A. Elmas, T. Tabel, Y. Özdemir, R. Otlu, H. G. (2016). Analysis of urine biomarkers for early determination of acute kidney injury in non septic and non asphyxiated critically ill preterm neonates. The Journal of Maternal-Fetal & Neonatal Medicine, 30(3), 302–308.en_US
dc.identifier.doi10.3109/14767058.2016.1171311en_US
dc.identifier.endpage308en_US
dc.identifier.issn1476-7058
dc.identifier.issue3en_US
dc.identifier.startpage302en_US
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.3109/14767058.2016.1171311
dc.identifier.urihttps://hdl.handle.net/11616/6652
dc.identifier.volume30en_US
dc.language.isoenen_US
dc.publisherThe Journal of Maternal-Fetal & Neonatal Medicineen_US
dc.relation.ispartofThe Journal of Maternal-Fetal & Neonatal Medicineen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcute kidney injuryen_US
dc.subjectKidney injury molecule–1en_US
dc.subjectNeutrophil gelatinase associate lipocalineen_US
dc.subjectPreterm infantsen_US
dc.subjectSistatin–Cen_US
dc.subjectUrineen_US
dc.titleAnalysis of urine biomarkers for early determination of acute kidney injury in non septic and non asphyxiated critically ill preterm neonatesen_US
dc.typeArticleen_US

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