Determination of gentamicin by using square wave anodic stripping voltammetry with poly (?-cyclodextrin-p-toluene sulfonic acid) modified glassy carbon electrode

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dc.contributor.authorBurc, Muammer
dc.contributor.authorTitretir Duran, Serap
dc.contributor.authorGungor, Oznur
dc.contributor.authorKaragozler, Ali Ersin
dc.date.accessioned2024-08-04T20:54:46Z
dc.date.available2024-08-04T20:54:46Z
dc.date.issued2024
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this study, an effective electrochemical method based on modified glassy carbon electrode was developed for the determination of gentamicin. Firstly, the poly beta-cyclodextrin-p-toluene sulfonic acid/glassy carbon electrode as gentamicin selective electrode was prepared by electropolymerization technique. In situ electropolymerization of beta-cyclodextrin and p-toluene sulfonic acid was conducted on bare glassy carbon electrode by controlled potential cycling. Characterization of the prepared poly beta-cyclodextrin-p-toluene sulfonic acid/glassy carbon electrode was performed using cyclic voltammetry and electrochemical impedance spectroscopy. Then, the effects of various parameters were investigated using square wave anodic stripping voltammetry in citrate buffer containing 4.0 mmol L-1 gentamicin. The calibration graph plotted over the range of 0.06-4.0 mmol L-1 gentamicin concentration showed high linearity. Correlation coefficient, detection limit and quantitation limit were obtained from the calibration graph as 0.9999, 3.7 mu mol L-1 and 12.4 mu mol L-1, respectively. According to these results, it is seen that the prepared poly beta-cyclodextrin-p-toluene sulfonic acid/glassy carbon electrode can be successfully used for the determination of gentamicin in many pharmacological, medical and biochemical applications.en_US
dc.description.sponsorshipUniversity Scientific Research Projects Coordination [FYL-2018-1504]en_US
dc.description.sponsorshipThe financing of this study is University Scientific Research Projects Coordination and it was supported by the project numbered FYL-2018-1504. GNS electrochemical reaction mechanism was suggested by Prof. Dr. UElkue Yilmaz.en_US
dc.identifier.doi10.1007/s00289-023-05011-0
dc.identifier.endpage6403en_US
dc.identifier.issn0170-0839
dc.identifier.issn1436-2449
dc.identifier.issue7en_US
dc.identifier.scopus2-s2.0-85173741995en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage6381en_US
dc.identifier.urihttps://doi.org/10.1007/s00289-023-05011-0
dc.identifier.urihttps://hdl.handle.net/11616/101616
dc.identifier.volume81en_US
dc.identifier.wosWOS:001081573200001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofPolymer Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGentamicinen_US
dc.subjectbeta-cyclodextrinen_US
dc.subjectp-toluene sulfonic aciden_US
dc.subjectGlassy carbon electrodeen_US
dc.subjectSensoren_US
dc.titleDetermination of gentamicin by using square wave anodic stripping voltammetry with poly (?-cyclodextrin-p-toluene sulfonic acid) modified glassy carbon electrodeen_US
dc.typeArticleen_US

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