Factors Associated with Low Bone Mineral Density at the Time of Diagnosis in Children with Celiac Disease

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dc.authoridÇamtosun, Emine/0000-0002-8144-4409
dc.authoridVarol, İlknur fatma/0000-0001-5212-218X
dc.authorwosidÇamtosun, Emine/AAE-3945-2020
dc.authorwosidVarol, İlknur fatma/ABH-6387-2020
dc.contributor.authorcamtosun, Emine
dc.contributor.authorVarol, Fatma Ilknur
dc.contributor.authorGungor, Suekrue
dc.contributor.authorSelimoglu, Mukadder Ayse
dc.date.accessioned2024-08-04T20:10:19Z
dc.date.available2024-08-04T20:10:19Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: It has been reported that bone mineral density (BMD) is decreased in children with Celiac disease (CD) compared to their healthy peers. The aim of this study was to reveal possible risk factors for low BMD in Turkish children newly diagnosed with CD. Methods: Eighty-six patients (2-18 years old) with CD were included in this retrospective study. The relationship between their lumbar BMD z-scores calculated according to their chronological age (CA) and height age (HA) and their clinical, laboratory [biochemical parameters, tissue transglutaminase antibody-IgA (TTGA) levels, human leukocyte antigen (HLA) types] and histopathological parameters were evaluated.Results: The mean age of the patients at diagnosis was 8.06 +/- 4.08 years. The BMD z-score CA was <=-2 standard deviation (SD) in 26.7% of the patients. The BMD z-score HA was <=-2 SD in 12.8% of the patients. The BMD z-score HA only correlated with their age at diagnosis of CD (rs value 0.269). However, there was no statistically difference between the BMD z-score HA >-2 SD and <=-2 SD subgroups regarding their clinical, laboratory and histopathological parameters. Conclusion: Low BMD is common in children with newly diagnosed CD. Age at diagnosis, gender, body size, Celiac symptoms, biochemical parameters, TTGA level, HLA type, and histopathological stage had no predictive values in terms of low BMD in this patient group.en_US
dc.identifier.doi10.4274/jcrpe.galenos.2022.2022-5-18
dc.identifier.endpage68en_US
dc.identifier.issn1308-5727
dc.identifier.issn1308-5735
dc.identifier.issue1en_US
dc.identifier.pmid36264034en_US
dc.identifier.scopus2-s2.0-85149053241en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage62en_US
dc.identifier.trdizinid1175478en_US
dc.identifier.urihttps://doi.org/10.4274/jcrpe.galenos.2022.2022-5-18
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1175478
dc.identifier.urihttps://hdl.handle.net/11616/92701
dc.identifier.volume15en_US
dc.identifier.wosWOS:000938263200009en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofJournal of Clinical Research in Pediatric Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLow bone mineral densityen_US
dc.subjectCeliac diseaseen_US
dc.subjectchildrenen_US
dc.subjectrisk factorsen_US
dc.titleFactors Associated with Low Bone Mineral Density at the Time of Diagnosis in Children with Celiac Diseaseen_US
dc.typeArticleen_US

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