The impact of thyroid-stimulating hormone levels in euthyroid women onintrauterine insemination outcome
Yükleniyor...
Dosyalar
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Bıomed central ltd, 236 grays ınn rd, floor 6, london wc1x 8hl, england
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: The aim of this study was to examine the effect of thyroid-stimulating hormone (TSH) levels on intrauterine insemination (IUI) outcomes among euthyroid women.
Methods: A retrospective cohort study was conducted. A total of 302 women who started their first IUI cycle in our fertility center were included in this study. The patients were categorized into two groups based on their preconception TSH values: 0.38-2.49 mIU/L and 2.50-4.99 mIU/L. The clinical pregnancy rate was the main outcome parameter. As secondary parameters, we evaluated the differences in spontaneous abortion rate, live-birth delivery rate, and perinatal outcomes according to the preconception TSH threshold (< 2.5 and < 5.00 mIU/L).
Results: There was no significant difference between the two groups with respect to clinical pregnancy, miscarriage, and live-birth rates with an odds ratio of 1.67 (95% CI: 0.79-3.53), 1.08 (95% CI: 0.09-13.1), and 1.79 (95% CI: 0.77-4.2), respectively. In addition, there were no significant differences in perinatal outcomes (gestation at delivery, birth weight, and neonatal intensive care unit-administration rate) between the two groups.
Conclusions: Our findings indicate that among euthyroid patients, preconception TSH values in the high-normal range (between 2.5 and 4.9 mIU/L) do not have a negative effect on IUI outcomes.
Açıklama
Anahtar Kelimeler
Pregnant-women, dısease, postpartum, management, hypothyroıdısm, establıshment, assocıatıon, dysfunctıon, ınfertılıty, guıdelınes
Kaynak
Bmc womens health
WoS Q Değeri
Scopus Q Değeri
Cilt
18
Sayı
0
Künye
Tuncay, G. Karaer, A . Coskun, EI . Baloglu, D. Tecellioglu, AN. (2018). The impact of thyroid-stimulating hormone levels in euthyroid women onintrauterine insemination outcome. Cilt:18.
