The impact of thyroid-stimulating hormone levels in euthyroid women onintrauterine insemination outcome

dc.contributor.authorTuncay, Gorkem
dc.contributor.authorKaraer, Abdullah
dc.contributor.authorCoskun, Ebru Inci
dc.contributor.authorBaloglu, Demet
dc.contributor.authorTecellioglu, Ayse Nihan
dc.date.accessioned2019-07-23T07:36:26Z
dc.date.available2019-07-23T07:36:26Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: The aim of this study was to examine the effect of thyroid-stimulating hormone (TSH) levels on intrauterine insemination (IUI) outcomes among euthyroid women. Methods: A retrospective cohort study was conducted. A total of 302 women who started their first IUI cycle in our fertility center were included in this study. The patients were categorized into two groups based on their preconception TSH values: 0.38-2.49 mIU/L and 2.50-4.99 mIU/L. The clinical pregnancy rate was the main outcome parameter. As secondary parameters, we evaluated the differences in spontaneous abortion rate, live-birth delivery rate, and perinatal outcomes according to the preconception TSH threshold (< 2.5 and < 5.00 mIU/L). Results: There was no significant difference between the two groups with respect to clinical pregnancy, miscarriage, and live-birth rates with an odds ratio of 1.67 (95% CI: 0.79-3.53), 1.08 (95% CI: 0.09-13.1), and 1.79 (95% CI: 0.77-4.2), respectively. In addition, there were no significant differences in perinatal outcomes (gestation at delivery, birth weight, and neonatal intensive care unit-administration rate) between the two groups. Conclusions: Our findings indicate that among euthyroid patients, preconception TSH values in the high-normal range (between 2.5 and 4.9 mIU/L) do not have a negative effect on IUI outcomes.en_US
dc.identifier.citationTuncay, G. Karaer, A . Coskun, EI . Baloglu, D. Tecellioglu, AN. (2018). The impact of thyroid-stimulating hormone levels in euthyroid women onintrauterine insemination outcome. Cilt:18.en_US
dc.identifier.doi10.1186/s12905-018-0541-0en_US
dc.identifier.endpage0en_US
dc.identifier.issue0en_US
dc.identifier.startpage0en_US
dc.identifier.urihttps://hdl.handle.net/11616/12860
dc.identifier.volume18en_US
dc.language.isoenen_US
dc.publisherBıomed central ltd, 236 grays ınn rd, floor 6, london wc1x 8hl, englanden_US
dc.relation.ispartofBmc womens healthen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPregnant-womenen_US
dc.subjectdıseaseen_US
dc.subjectpostpartumen_US
dc.subjectmanagementen_US
dc.subjecthypothyroıdısmen_US
dc.subjectestablıshmenten_US
dc.subjectassocıatıonen_US
dc.subjectdysfunctıonen_US
dc.subjectınfertılıtyen_US
dc.subjectguıdelınesen_US
dc.titleThe impact of thyroid-stimulating hormone levels in euthyroid women onintrauterine insemination outcomeen_US
dc.typeArticleen_US

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