Neuroendocrine tumors

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dc.authorscopusid54582267900
dc.contributor.authorÇikim-Sertkaya A.
dc.date.accessioned2024-08-04T19:59:41Z
dc.date.available2024-08-04T19:59:41Z
dc.date.issued2007
dc.departmentİnönü Üniversitesien_US
dc.description.abstractDiffuse neuroendocrine system is an extremely extended system which spread out through whole body. Despite the neuroendocrine tumors (NET) rising from this system can originate from any tissue or organ; gastro-entero-pancreatic region (GEP) especially pancreas is the most common site (70 %). Whitin this region 50 % of the tumors are functioning that means these tumors secreat one or more hormones. The functioning tumors are diagnosed with their specific semptoms which depend on the hormone secreted from. Whereas non-functioning tumors are diagnosed with their mass effects. Enterochromaffin cell carsinoid (EC) is the most frequent (55 %), which followed by insulinoma (15 %), gastrinoma (12 %), and argyrophilic enterochromaffin cell like carcinoid (3.2%), VIPoma (1.4 %), glucagonoma (1.2 %) and somatostatinoma (5.2 %). Approximately 10 % of the functioning GEP-NET's are associated with multiple endocrine neoplasia (MEN) syndromes which suggested to be inherited. Where as 60 % of the sporadic cases are nalignant, the incidence of malignancy in hereditary forms are lesser (45 %). Although the 5 year survival rates are also better in hereditary tumors with a 15 years of life expectancy, the rates changes between 11 to 40 % whitin sporadic cases.en_US
dc.identifier.endpage82en_US
dc.identifier.issn1016-5134
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-34447622117en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage78en_US
dc.identifier.urihttps://hdl.handle.net/11616/90827
dc.identifier.volume19en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofSENDROMen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectargyrophilic enterochromaffin cell like carcinoiden_US
dc.subjectarticleen_US
dc.subjectbronchospasmen_US
dc.subjectcarcinoiden_US
dc.subjectclinical featureen_US
dc.subjectdisease associationen_US
dc.subjectenterochromaffin cellen_US
dc.subjectflushingen_US
dc.subjectgastrinomaen_US
dc.subjectglucagonomaen_US
dc.subjectheredityen_US
dc.subjecthumanen_US
dc.subjectinsulinomaen_US
dc.subjectintestineen_US
dc.subjectlife expectancyen_US
dc.subjectmultiple endocrine neoplasiaen_US
dc.subjectneuroendocrine tumoren_US
dc.subjectpancreasen_US
dc.subjectrashen_US
dc.subjectsomatostatinomaen_US
dc.subjectstomachen_US
dc.subjectsurvival rateen_US
dc.subjectsurvival timeen_US
dc.subjectsymptomen_US
dc.subjectvipomaen_US
dc.subjectwheezingen_US
dc.titleNeuroendocrine tumorsen_US
dc.title.alternativeNöroendokrin tümörleren_US
dc.typeArticleen_US

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