Magnesium Sulphate Given Intraoperatively Can Reduce Blood Loss Without Effecting the Coagulation System
Küçük Resim Yok
Tarih
2003
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The prevention of bleeding that will occur during surgical procedure is very important for the surgeon and for the anaesthesiologist. The aim of the current study is to determine the effects of magnesium that can be used in controlled hypotension on amount of bleeding, surgeon bleeding score, coagulation tests and hemodynamic parameters. This study was performed in fourty ASA physical score I adult patients who underwent septorhinoplasty procedures. Patients were divided as Magnesium (n=20) and Control groups (n=20). The patients in the magnesium group were given a bolus dose of magnesium sulphate 50 mg kg-1 in 50 mL of serum physiologic solution and had magnesium infusion at a rate of 15 mg kg-1 h-1 whereas the latients in the control group received a bolus of 50 mL of serum physiologic solution and infusion. During the procedure hemodynamic parameters were recorded in every 5 minutes. Venous blood samples were taken for analysing serum magnesium, calcium, hemoglobin and fibrinogen levels, prothrombin time, partial thromboplastine time, INR, and platelet count before and after the operation and at the postoperative 6th hour. In Magnesium group, the of serum fibrinogen level between before operation value and after operation value was lower than the difference of serum fibrinogen level between before operation value and after operation value in placebo group (p<0.05). The amount of bleeding in magnesium group was 50 mL less than the amount of bleeding in the plasebo group but this was not significant (p>0.0.5). The additional narcotic use and surgeon bleeding scores between two groups were significantly different (p<0.05). As a conclusion; we suggest that magnesium sulphate which is not contraindicated in ASA physical score I patients can provide a stabil blood pressure at the given doses and can affect surgeon bleeding score at a positive manner without any significant effect on the coagulation system.
Açıklama
Anahtar Kelimeler
Blood coagulation, Blood loss, surgical, Hemodynamics, Magnesium
Kaynak
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
31
Sayı
10
