Magnesium Sulphate Given Intraoperatively Can Reduce Blood Loss Without Effecting the Coagulation System

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dc.authorscopusid6507063121
dc.authorscopusid34569135700
dc.authorscopusid7006384185
dc.authorscopusid6701613323
dc.authorscopusid7004486274
dc.contributor.authorHasçalik M.
dc.contributor.authorDurmuş M.
dc.contributor.authorÖztürk E.
dc.contributor.authorTo?al T.
dc.contributor.authorErsoy M.Ö.
dc.date.accessioned2024-08-04T20:02:10Z
dc.date.available2024-08-04T20:02:10Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe prevention of bleeding that will occur during surgical procedure is very important for the surgeon and for the anaesthesiologist. The aim of the current study is to determine the effects of magnesium that can be used in controlled hypotension on amount of bleeding, surgeon bleeding score, coagulation tests and hemodynamic parameters. This study was performed in fourty ASA physical score I adult patients who underwent septorhinoplasty procedures. Patients were divided as Magnesium (n=20) and Control groups (n=20). The patients in the magnesium group were given a bolus dose of magnesium sulphate 50 mg kg-1 in 50 mL of serum physiologic solution and had magnesium infusion at a rate of 15 mg kg-1 h-1 whereas the latients in the control group received a bolus of 50 mL of serum physiologic solution and infusion. During the procedure hemodynamic parameters were recorded in every 5 minutes. Venous blood samples were taken for analysing serum magnesium, calcium, hemoglobin and fibrinogen levels, prothrombin time, partial thromboplastine time, INR, and platelet count before and after the operation and at the postoperative 6th hour. In Magnesium group, the of serum fibrinogen level between before operation value and after operation value was lower than the difference of serum fibrinogen level between before operation value and after operation value in placebo group (p<0.05). The amount of bleeding in magnesium group was 50 mL less than the amount of bleeding in the plasebo group but this was not significant (p>0.0.5). The additional narcotic use and surgeon bleeding scores between two groups were significantly different (p<0.05). As a conclusion; we suggest that magnesium sulphate which is not contraindicated in ASA physical score I patients can provide a stabil blood pressure at the given doses and can affect surgeon bleeding score at a positive manner without any significant effect on the coagulation system.en_US
dc.identifier.endpage510en_US
dc.identifier.issn1304-0871
dc.identifier.issue10en_US
dc.identifier.scopus2-s2.0-19244373487en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage504en_US
dc.identifier.urihttps://hdl.handle.net/11616/91444
dc.identifier.volume31en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyon Dernegi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBlood coagulationen_US
dc.subjectBlood lossen_US
dc.subjectsurgicalen_US
dc.subjectHemodynamicsen_US
dc.subjectMagnesiumen_US
dc.titleMagnesium Sulphate Given Intraoperatively Can Reduce Blood Loss Without Effecting the Coagulation Systemen_US
dc.title.alternativeİntraoperatif Verilen Magnezyum Sülfat Koagülasyon Sistemini Etkilemeden Kan Kaybini Azaltabiliren_US
dc.typeArticleen_US

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