Platelet Counts in Children With Henoch-Schonlein PurpuraRelationship to Renal Involvement
Küçük Resim Yok
Tarih
2016
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
BackgroundThe aim of this study is to identify the clinical and laboratory risk factors for renal involvement and to determine the relationship between platelet counts and renal involvement in (Henoch-Schonlein purpura) HSP patients. MethodsWe reviewed the medical records of 107 children with HSP according to Eular/Press diagnostic criteria. Clinical and laboratory parameters for renal involvement were evaluated and compared to no renal involvement. ResultsA retrospective study consisted of 107 children, 61 boys (57%), and 46 girls (43%). Twenty-eight of the 107 patients (26.1%) had renal involvement. The mean platelet count was significantly higher in patients with renal involvement when compared to patients without renal involvement (P = 0.001). The multivariate logistic regression analysis identified that age (P = 0.022), sex (P = 0.037), gastrointestinal involvement (P=0.019), and platelet count (P = 0.019) were significantly associated with the renal involvement of HSP. The platelet count was predictive of renal involvement, which had odds ratio of 1.0, and achieved area under the curve of 0.66 for predicting the renal involvement within the acute stage of HSP (P=0.009). ConclusionOur study indicated that age, sex, gastrointestinal involvement, and platelet count were significant risk factors of renal involvement of HSP.
Açıklama
Anahtar Kelimeler
child, Henoch-Schonlein purpura, platelet counts, renal involvement
Kaynak
Journal of Clinical Laboratory Analysis
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
30
Sayı
1
