Platelet Counts in Children With Henoch-Schonlein PurpuraRelationship to Renal Involvement

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dc.authoridElmas, Ahmet Taner/0000-0002-9749-6115;
dc.authorwosidTabel, Yilmaz/AAF-9801-2020
dc.authorwosidElmas, Ahmet Taner/ABI-1338-2020
dc.authorwosidELMAS, Ahmet Taner/W-4101-2017
dc.contributor.authorElmas, Ahmet Taner
dc.contributor.authorTabel, Yilmaz
dc.date.accessioned2024-08-04T20:41:26Z
dc.date.available2024-08-04T20:41:26Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackgroundThe aim of this study is to identify the clinical and laboratory risk factors for renal involvement and to determine the relationship between platelet counts and renal involvement in (Henoch-Schonlein purpura) HSP patients. MethodsWe reviewed the medical records of 107 children with HSP according to Eular/Press diagnostic criteria. Clinical and laboratory parameters for renal involvement were evaluated and compared to no renal involvement. ResultsA retrospective study consisted of 107 children, 61 boys (57%), and 46 girls (43%). Twenty-eight of the 107 patients (26.1%) had renal involvement. The mean platelet count was significantly higher in patients with renal involvement when compared to patients without renal involvement (P = 0.001). The multivariate logistic regression analysis identified that age (P = 0.022), sex (P = 0.037), gastrointestinal involvement (P=0.019), and platelet count (P = 0.019) were significantly associated with the renal involvement of HSP. The platelet count was predictive of renal involvement, which had odds ratio of 1.0, and achieved area under the curve of 0.66 for predicting the renal involvement within the acute stage of HSP (P=0.009). ConclusionOur study indicated that age, sex, gastrointestinal involvement, and platelet count were significant risk factors of renal involvement of HSP.en_US
dc.identifier.doi10.1002/jcla.21817
dc.identifier.endpage74en_US
dc.identifier.issn0887-8013
dc.identifier.issn1098-2825
dc.identifier.issue1en_US
dc.identifier.pmid25385472en_US
dc.identifier.scopus2-s2.0-84954041243en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage71en_US
dc.identifier.urihttps://doi.org/10.1002/jcla.21817
dc.identifier.urihttps://hdl.handle.net/11616/97111
dc.identifier.volume30en_US
dc.identifier.wosWOS:000367946500010en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Clinical Laboratory Analysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectchilden_US
dc.subjectHenoch-Schonlein purpuraen_US
dc.subjectplatelet countsen_US
dc.subjectrenal involvementen_US
dc.titlePlatelet Counts in Children With Henoch-Schonlein PurpuraRelationship to Renal Involvementen_US
dc.typeArticleen_US

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