Nutritional rickets in Turkish and refugee children aged 0-2: an increasing problem despite vitamin D prophylaxis

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dc.authoridDundar, Ismail/0000-0003-1468-6405
dc.authoridBuyukavci, Mehmet Akif/0000-0001-6884-1832
dc.authorwosidDundar, Ismail/ABG-2027-2021
dc.authorwosidBuyukavci, Mehmet Akif/HCH-2615-2022
dc.contributor.authorDundar, Ismail
dc.contributor.authorBuyukavci, Mehmet Akif
dc.date.accessioned2024-08-04T20:10:21Z
dc.date.available2024-08-04T20:10:21Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground. Nutritional rickets (NR) is still a major problem and is exacerbated by an increasing influx of immigrants. In this study, Turkish and immigrant cases followed with the diagnosis of NR in our pediatric endocrinology clinic were retrospectively evaluated. Methods. Detailed data of cases diagnosed with NR between 2013 and 2020 and followed for at least six months were reviewed. Results. In the study period, 77 cases of NR were identified. Turkish children constituted 76.6% (n=59) while 18 (23.4%) were immigrant children. The mean age at diagnosis was 8.1 & PLUSMN;7.8 months, 32.5% (n=25) were female, and 67.5% (n=52) were male. The 25-hydroxyvitamin D3 was below normal in all patients, with a mean value of 4.3 & PLUSMN;2.6 ng/mL. Parathyroid hormone (PTH) was above normal in all and the mean value was 301.7 & PLUSMN;139.3 pg/ mL. While there were 3.9 cases of NR in 10,000 endocrine clinic patients in 2013, this rate increased more than four-fold to 15.7 patients in 2019. Conclusions. Despite the vitamin D prophylaxis program in Turkiye, NR is seen significantly more frequently in recent years, which may be associated with an increasing number of refugees. High PTH levels indicate the severity of NR cases admitted to our clinic. However, clinically significant NR is only the tip of the iceberg and the true burden of subclinical rickets is unknown. Increasing compliance with the vitamin D supplementation in and Turkish children is for the of nutritional rickets.en_US
dc.identifier.doi10.24953/turkjped.2022.860
dc.identifier.endpage415en_US
dc.identifier.issn0041-4301
dc.identifier.issue3en_US
dc.identifier.pmid37395960en_US
dc.identifier.scopus2-s2.0-85164210259en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage406en_US
dc.identifier.trdizinid1186243en_US
dc.identifier.urihttps://doi.org/10.24953/turkjped.2022.860
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1186243
dc.identifier.urihttps://hdl.handle.net/11616/92728
dc.identifier.volume65en_US
dc.identifier.wosWOS:001025408400006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish J Pediatricsen_US
dc.relation.ispartofTurkish Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectchildrenen_US
dc.subjectimmigranten_US
dc.subjectnutritional ricketsen_US
dc.subjectvitamin D deficiencyen_US
dc.titleNutritional rickets in Turkish and refugee children aged 0-2: an increasing problem despite vitamin D prophylaxisen_US
dc.typeArticleen_US

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