Hybrid PLGA nanoparticles as advanced drug delivery and theranostic applications

Basit Öğe Kaydı
dc.authorscopusid57212018375
dc.authorscopusid6603768177
dc.contributor.authorTonbul H.
dc.contributor.authorÇapan Y.
dc.date.accessioned2024-08-04T20:03:54Z
dc.date.available2024-08-04T20:03:54Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractNanoparticles are ultradispersed solid supramolecular structures made of organic or inorganic materials, preferably smaller than 500nm. These structures hold great potential for improving the pharmacokinetics and therapeutic index of several drugs including small molecules, genes, peptide- and protein-based therapeutics, and diagnostic agents. Generally, these payloads are covalently or electrostatically grafted on the surface or encapsulated within the nanocarriers. Although each nanocarrier has different advantages and drawbacks depending on its material, and none of them are fully superior to others, poly(lactic-co-glycolic acid) (PLGA)-based nanoparticles are one of the most investigated among them. To overcome the drawbacks of conventional nanocarriers, using more than one nanocarrier material or a complete nanoparticle system to obtain a single nanosystem has become a focus in the last few decades. These systems are called hybrid nanoparticle systems and generally, they have all the benefits of the source materials and component nanoparticle systems. This chapter aims to provide an overview of hybrid nanoparticles and discusses PLGA-based hybrid nanoparticles and their drug delivery and theranostic applications in depth. © 2023 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/B978-0-323-91215-0.00017-0
dc.identifier.endpage431en_US
dc.identifier.isbn9780323912150
dc.identifier.isbn9780323914314
dc.identifier.scopus2-s2.0-85168918494en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage417en_US
dc.identifier.urihttps://doi.org/10.1016/B978-0-323-91215-0.00017-0
dc.identifier.urihttps://hdl.handle.net/11616/92199
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofPoly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Deliveryen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCore-shellen_US
dc.subjectDrug deliveryen_US
dc.subjectHybrid nanoparticlesen_US
dc.subjectPLGAen_US
dc.subjectTanker and bargeen_US
dc.titleHybrid PLGA nanoparticles as advanced drug delivery and theranostic applicationsen_US
dc.typeBook Chapteren_US

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