Prediction of spontaneous preterm delivery in women with preterm labor: Analysis of interleukin-17, migration inhibitory factor, monocyte chemotactic protein-1 in maternal serum and cervicovaginal fluid

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dc.authoridKaraer, Abdullah/0000-0002-2010-6211
dc.authoridCelik, ebru/0000-0002-0774-4294;
dc.authorwosidKaraer, Abdullah/ABI-4667-2020
dc.authorwosidÖzerol, İbrahim Halil/ABI-8015-2020
dc.authorwosidCelik, ebru/X-4343-2019
dc.authorwosidÖZEROL, ELİF/AAA-6707-2021
dc.contributor.authorKaraer, Abdullah
dc.contributor.authorCelik, Onder
dc.contributor.authorDogan, Cagdas
dc.contributor.authorOzerol, Ibrahim Halil
dc.contributor.authorSimsek, Omer Yavuz
dc.contributor.authorCelik, Ebru
dc.contributor.authorOzerol, Elif
dc.date.accessioned2024-08-04T20:36:03Z
dc.date.available2024-08-04T20:36:03Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: To analyze whether, interleukin (IL)-17, migration inhibitory factor (MIF), monocyte chemotactic protein (MCP)-1 in maternal serum and cervicovaginal fluid, can identify women in preterm labor with intact membranes who will deliver spontaneously within 7 days of sampling. Material and Methods: Forty-four (44) singleton pregnancies between 26-34 weeks of gestation that had threatened preterm labor, enrolled from October 2010 and October 2011. Cervical length was evaluated with transvaginal ultrasonography. Serum and cervicovaginal fluid IL-17, MIF, and MCP-1 were measured with the use of enzyme linked immune assay. Subjects were followed up for premature delivery within 7 days. Results: Seventeen of 44 patients (39%) had preterm delivery and 15 of 44 (34%) delivered within 7 day from admission. The only significant predictor for establishment of preterm delivery within 7 days was cervical length. The median cervical length was 18 mm (range: 5-27) in women who delivered in 7 days and 27 mm (range: 9-44) in women who delivered beyond 7 days of presentation (p-0.001). There was no association between serum and cervicovaginal fluid IL-17, MIF and MCP-1 levels and preterm delivery within 7 days. Conclusions: Cervical length could serve as a predictive factor for the progress of threatened preterm labor to true preterm labor. Serum and cervicovaginal fluid IL-17, MIF and MCP-1 can not be used to differentiate true preterm labor.en_US
dc.identifier.doi10.5505/tjb.2012.96158
dc.identifier.endpage161en_US
dc.identifier.issn0250-4685
dc.identifier.issn1303-829X
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84864466950en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage156en_US
dc.identifier.urihttps://doi.org/10.5505/tjb.2012.96158
dc.identifier.urihttps://hdl.handle.net/11616/95760
dc.identifier.volume37en_US
dc.identifier.wosWOS:000307444200007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofTurkish Journal of Biochemistry-Turk Biyokimya Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCervical lengthen_US
dc.subjectinterleukin-17en_US
dc.subjectmigration inhibitory factoren_US
dc.subjectmonocyte chemotactic protein-1en_US
dc.subjectpreterm birthen_US
dc.titlePrediction of spontaneous preterm delivery in women with preterm labor: Analysis of interleukin-17, migration inhibitory factor, monocyte chemotactic protein-1 in maternal serum and cervicovaginal fluiden_US
dc.typeArticleen_US

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