Effect of nanosized TiO2 particles on the development of Xenopus laevis embryos

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dc.contributor.authorBirhanli, Ayse
dc.contributor.authorEmre, Fatma Bilge
dc.contributor.authorSayilkan, Funda
dc.contributor.authorGungordu, Abbas
dc.date.accessioned2020-07-16T09:21:14Z
dc.date.available2020-07-16T09:21:14Z
dc.date.issued2014
dc.departmentİnönü Üniversitesien_US
dc.descriptionTURKISH JOURNAL OF BIOLOGY Volume: 38 Issue: 2 Pages: 283-288 DOI: 10.3906/biy-1307-37 Published: 2014 Document Type:Articleen_US
dc.description.abstractThis paper reports the toxic properties of nano-TiO2 on 2 different early life stages of Xenopus laevis. Synthesis of nano-TiO2 particles was carried out by the hydrothermal method. Characterization of nanoparticles was performed using spectral techniques including X-ray diffraction, scanning electron microscopy, and a particle-size analyzer. Embryos at the 8th stage and tadpoles at the 46th stage were exposed to 7 concentrations of nano-TiO2 in the range of 5 to 320 ppm. After 96 h of exposure, the mortality percentage of each exposure concentration was calculated and the activity of enzyme biomarkers acetylcholinesterase, carboxylesterase, glutathione S-transferase, glutathione reductase, lactate dehydrogenase, and aspartate aminotransferase were determined in living embryos and tadpoles. None of the tested concentrations of TiO2 caused statistically significant mortality or malformation (only for the embryo test) as compared to the control groups. Furthermore, we did not observe any significant changes in enzyme activities in tadpole samples from the 46th stage, although some minor changes not related to the concentrations were observed in embryos.en_US
dc.description.sponsorshipInonu University BAPB-2011/31en_US
dc.identifier.citationBirhanli, A., Emre, F.B., Sayilkan, F., Gungordu, A. Effect of nanosized TiO2 particles on the development of Xenopus laevis embryos. (2014). TURKISH JOURNAL OF BIOLOGY.en_US
dc.identifier.doi10.3906/biy-1307-37en_US
dc.identifier.endpage288en_US
dc.identifier.issn1300-0152
dc.identifier.issn1303-6092
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84896288671en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage283en_US
dc.identifier.trdizinid159862en_US
dc.identifier.urihttps://doi.org/10.3906/biy-1307-37
dc.identifier.urihttps://hdl.handle.net/11616/16999
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/159862
dc.identifier.volume38en_US
dc.identifier.wosWOS:000332944300014en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY,en_US
dc.relation.ispartofTurkish Journal of Biologyen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjecthydrothermal processen_US
dc.subjectXenopus laevisen_US
dc.subjectbiomarkeren_US
dc.subjectTiO2en_US
dc.titleEffect of nanosized TiO2 particles on the development of Xenopus laevis embryosen_US
dc.typeArticleen_US

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