Biotechnology applications in clinical trials

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Tarih

2022

Dergi Başlığı

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Yayıncı

Elsevier

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

It is known that genetic factors, living conditions, and dietary habits affect a person's life expectancy and quality. Changes in these factors can lead to deterioration of health and pathogeny. Although the causes of the disease cannot be eliminated, different methods have been developed to fight the disease. The advancement of biotechnology has allowed the development of drugs, which are synthetic or biological origin medicinal products. Biological medicinal products are defined as products derived from living organisms or containing their components. In these products, it is aimed to bring functions to the cell by manipulation of genetic material. Advanced and innovative methodologies used in genomics, pharmaceuticals, DNA sequencing, cell culture, interference RNA and genome editing, gene sequencing, stem cells for regenerative medicine, tissue engineering play an important role to understand and develop the medical biotechnology. These biological products include proteins that act on different proteins and cellular processes in the body, genes that control the production of vital proteins, cells that produce substances necessary to suppress or activate immune system elements. This chapter provides a basic overview of the latest developments in clinical trials from samples of different classes of biotechnological products such as nonviral/viral gene therapy and peptide/protein-based drugs. © 2022 Elsevier Inc. All rights reserved.

Açıklama

Anahtar Kelimeler

Clinical trials, Gene therapy in clinical trials, Peptide drugs, Protein drugs, Synthetic biology

Kaynak

Biotechnology in Healthcare, Volume 2: Applications and Initiatives

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Scopus Q Değeri

N/A

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