Biotechnology applications in clinical trials

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dc.authorscopusid13205091800
dc.authorscopusid56682786000
dc.authorscopusid26436187600
dc.authorscopusid57993343800
dc.contributor.authorBüyükköroğlu G.
dc.contributor.authorŞenel B.
dc.contributor.authorŞalva E.
dc.contributor.authorÇalışkan B.
dc.date.accessioned2024-08-04T20:03:54Z
dc.date.available2024-08-04T20:03:54Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIt is known that genetic factors, living conditions, and dietary habits affect a person's life expectancy and quality. Changes in these factors can lead to deterioration of health and pathogeny. Although the causes of the disease cannot be eliminated, different methods have been developed to fight the disease. The advancement of biotechnology has allowed the development of drugs, which are synthetic or biological origin medicinal products. Biological medicinal products are defined as products derived from living organisms or containing their components. In these products, it is aimed to bring functions to the cell by manipulation of genetic material. Advanced and innovative methodologies used in genomics, pharmaceuticals, DNA sequencing, cell culture, interference RNA and genome editing, gene sequencing, stem cells for regenerative medicine, tissue engineering play an important role to understand and develop the medical biotechnology. These biological products include proteins that act on different proteins and cellular processes in the body, genes that control the production of vital proteins, cells that produce substances necessary to suppress or activate immune system elements. This chapter provides a basic overview of the latest developments in clinical trials from samples of different classes of biotechnological products such as nonviral/viral gene therapy and peptide/protein-based drugs. © 2022 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/B978-0-323-90042-3.00003-7
dc.identifier.endpage195en_US
dc.identifier.isbn9780323900423
dc.identifier.isbn9780323903646
dc.identifier.scopus2-s2.0-85143304557en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage163en_US
dc.identifier.urihttps://doi.org/10.1016/B978-0-323-90042-3.00003-7
dc.identifier.urihttps://hdl.handle.net/11616/92197
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofBiotechnology in Healthcare, Volume 2: Applications and Initiativesen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectClinical trialsen_US
dc.subjectGene therapy in clinical trialsen_US
dc.subjectPeptide drugsen_US
dc.subjectProtein drugsen_US
dc.subjectSynthetic biologyen_US
dc.titleBiotechnology applications in clinical trialsen_US
dc.typeBook Chapteren_US

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