Evaluation of protective effects of verapamil against lens epithelial tissue injury induced by irradiation in rats

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dc.authorscopusid6603280726
dc.authorscopusid6603777920
dc.authorscopusid7004027424
dc.authorscopusid35751057400
dc.authorscopusid13205562700
dc.authorscopusid35569663600
dc.authorscopusid36698899000
dc.contributor.authorBatçio?lu K.
dc.contributor.authorErkal H.S.
dc.contributor.authorSerIn M.
dc.contributor.authorUyumlu A.B.
dc.contributor.authorYücel N.
dc.contributor.authorYildirim B.
dc.contributor.authorSatilmiş B.
dc.date.accessioned2024-08-04T20:02:10Z
dc.date.available2024-08-04T20:02:10Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this study, we investigated the possible protectant effects of verapamil against lens epithelial tissue injury induced by irradiation in rats. Forty female Wistar Albino rats were divided into four groups (n=10). Group 1 received 10 mg/kg verapamil and underwent 20 Gy irradiation. Group 2 received no verapamil and underwent 20 Gy irradiation. Group 3 received 10 mg/kg verapamil and underwent sham irradiation. Group 4 received no verapamil and underwent sham irradiation. The lens tissues were dissected and measured malondialdehyde levels in all groups. The mean malondialdehyde levels (nmol/mg prt) were determined as 5,59 for Group 1, 7,04 for Group 2, 3,95 for Group 3 and 3,25 for Group 4. In conclusion, we can suggest that verapamil as a protectant agent against radiation induced lens epithelial tissue injury.en_US
dc.identifier.endpage272en_US
dc.identifier.issn1304-530X
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-78649815596en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage267en_US
dc.identifier.urihttps://hdl.handle.net/11616/91464
dc.identifier.volume7en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherTurkish Pharmacists Associationen_US
dc.relation.ispartofTurkish Journal of Pharmaceutical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLens injuryen_US
dc.subjectLipid peroxidationen_US
dc.subjectRadiationen_US
dc.subjectVerapamilen_US
dc.titleEvaluation of protective effects of verapamil against lens epithelial tissue injury induced by irradiation in ratsen_US
dc.title.alternativeRatlarda Radyasyonla indüklenen Lens Epitel Doku Hasarma Karşı Verapamil'in Koruyucu Etkilerinin De?erlendirilmesien_US
dc.typeArticleen_US

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