Pituitary volume in patients with panic disorder

Basit Öğe Kaydı
dc.contributor.authorKartalcı, Şükrü
dc.contributor.authorDoğan, Metin
dc.contributor.authorÜnal, Süheyla
dc.contributor.authorÖzcan, Abdulcemal
dc.contributor.authorÖzdemir, Serdal
dc.contributor.authorAtmaca, Murad
dc.date.accessioned2017-05-20T06:57:02Z
dc.date.available2017-05-20T06:57:02Z
dc.date.issued2011
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPanic patients have many functional deficiencies in the hypothalamic–pituitary–adrenal (HPA) axis. Previous studies have shown changed pituitary gland volume in some psychiatric disorders that have functional deficiencies in the HPA axis. However, to date no study has evaluated the pituitary gland volume in patients with panic disorder (PD). We investigated the pituitary gland volume in patients with PD (n= 27) and ageand sex-matched healthy controls (n= 27), using 1.5-T magnetic resonance imaging in this study. Analysis showed that patients with PD had significantly smaller pituitary volume compared to healthy subjects. Patients with agoraphobia especially had a significantly smaller pituitary volume than patients without agoraphobia. There was a significant relationship between the pituitary volume and both the severity of symptoms and the illness duration in the patient group. The results show that patients with PD have reduced pituitary volume, which may reflect the functional abnormalities seen in this disorder. These findings may help us better understand the pathology of PD.en_US
dc.identifier.citationKartalcı, Ş. Doğan, M. Ünal, S. Özcan, A. Özdemir, S. Atmaca, M. (2011). Pituitary volume in patients with panic disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 35(1), 203–207.en_US
dc.identifier.doi10.1016/j.pnpbp.2010.11.005en_US
dc.identifier.endpage207en_US
dc.identifier.issn02785846
dc.identifier.issue1en_US
dc.identifier.startpage203en_US
dc.identifier.urihttp://linkinghub.elsevier.com/retrieve/pii/S0278584610004203
dc.identifier.urihttps://hdl.handle.net/11616/6913
dc.identifier.volume35en_US
dc.language.isoOtheren_US
dc.publisherProgress in Neuro-Psychopharmacology and Biological Psychiatryen_US
dc.relation.ispartofProgress in Neuro-Psychopharmacology and Biological Psychiatryen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHPA axisen_US
dc.subjectMagnetic resonance imagingen_US
dc.subjectPanic disorderen_US
dc.subjectPituitary gland volumeen_US
dc.titlePituitary volume in patients with panic disorderen_US
dc.typeArticleen_US

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