The effect of the addition of clonidine to lidocaine during regional intravenous anaesthesia
Küçük Resim Yok
Tarih
2003
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Dergi Başlığı
Dergi ISSN
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Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Intravenous regional anaesthesia (IVRA), is a simple and convenient anaesthetic method that can be used in extremity surgeries for surgical analgesia. But absence of postoperative analgesic effect is an important disadvantage of this method. In this study, we aimed to evaluate the addition of clonidine to lidocaine on quality of peroperative analgesia in IVRA. After obtaining the Ethics Commitee approval, ASA I-II class, 40 patients undergoing elective surgery included to the study. Following Esmarch bandage and inflating of proximal tourniquet 100 mmHg over the systolic arterial pressure, cases divided into lidocaine 4 mg kg-1 (Group A, n=20) and lidocaine 4 mg kg-1 + clonidine 0.5 ?g kg-1 (Group B, n=20) groups. Ten minutes after the injection, proximal tourniquet deflated and distal tourniquet inflated. Preoperative basal measurements and heart rate and blood pressures were recorded 5 times with 2 minutes intervals after tourniquet deflation. VAS scores and sedation scores were evaluated in the first and second hours. Patient's first analgesic taking time was recorded. No significant statistical differences were detected in level of analgesia during operation between groups. Mean heart rate did not changed between groups after tourniquet deflation. Blood pressure values in group B, both within group and between groups were lower (p<0.05). VAS averages were lower in first and second hours in group B (p<0.05). In group B, the first analgesic taking time was longer than group A (p<0.05). We concluded that during IVRA, adding clonidine to lidocaine increases the analgesia quality after tourniquet deflation and prolongs the first analgesic need of cases.
Açıklama
Anahtar Kelimeler
Clonidine, Intravenous regional anaesthesia, Lidocaine
Kaynak
Turk Anesteziyoloji ve Reanimasyon
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
31
Sayı
2