The effect of the addition of clonidine to lidocaine during regional intravenous anaesthesia

dc.authorscopusid34569135700
dc.authorscopusid6504578293
dc.authorscopusid55898201200
dc.authorscopusid6506174296
dc.authorscopusid7004486274
dc.contributor.authorDurmuş M.
dc.contributor.authorTüköz A.
dc.contributor.authorGülhaş N.
dc.contributor.authorKaraaslan E.
dc.contributor.authorErsoy M.Ö.
dc.date.accessioned2024-08-04T20:00:36Z
dc.date.available2024-08-04T20:00:36Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntravenous regional anaesthesia (IVRA), is a simple and convenient anaesthetic method that can be used in extremity surgeries for surgical analgesia. But absence of postoperative analgesic effect is an important disadvantage of this method. In this study, we aimed to evaluate the addition of clonidine to lidocaine on quality of peroperative analgesia in IVRA. After obtaining the Ethics Commitee approval, ASA I-II class, 40 patients undergoing elective surgery included to the study. Following Esmarch bandage and inflating of proximal tourniquet 100 mmHg over the systolic arterial pressure, cases divided into lidocaine 4 mg kg-1 (Group A, n=20) and lidocaine 4 mg kg-1 + clonidine 0.5 ?g kg-1 (Group B, n=20) groups. Ten minutes after the injection, proximal tourniquet deflated and distal tourniquet inflated. Preoperative basal measurements and heart rate and blood pressures were recorded 5 times with 2 minutes intervals after tourniquet deflation. VAS scores and sedation scores were evaluated in the first and second hours. Patient's first analgesic taking time was recorded. No significant statistical differences were detected in level of analgesia during operation between groups. Mean heart rate did not changed between groups after tourniquet deflation. Blood pressure values in group B, both within group and between groups were lower (p<0.05). VAS averages were lower in first and second hours in group B (p<0.05). In group B, the first analgesic taking time was longer than group A (p<0.05). We concluded that during IVRA, adding clonidine to lidocaine increases the analgesia quality after tourniquet deflation and prolongs the first analgesic need of cases.en_US
dc.identifier.endpage103en_US
dc.identifier.issn1016-5150
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-17644439201en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage100en_US
dc.identifier.urihttps://hdl.handle.net/11616/90843
dc.identifier.volume31en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectClonidineen_US
dc.subjectIntravenous regional anaesthesiaen_US
dc.subjectLidocaineen_US
dc.titleThe effect of the addition of clonidine to lidocaine during regional intravenous anaesthesiaen_US
dc.title.alternativeRejiyonal i?ntravenöz anestezide lidokaine i?lave edilen klonidinin postoperatif analjezik etkisien_US
dc.typeArticleen_US

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