Evaluation of the effect of chronic smoking habit on corneal endothelial cells, central corneal thickness and dry eye tests

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2019

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info:eu-repo/semantics/openAccess

Özet

Aim: The aim of our study was to evaluate the effects of chronic smoking habit on corneal endothelial cells, central corneal thickness, and dry eye tests. Material and Methods: A total of 160 eyes of 160 chronic smokers and 160 eyes of 160 control cases were included in the study. The smokers were grouped into 4 groups according to pack-year smoking as follows: 0-10, 10-20, 20-30, >30. Endothelial cell density (CD), average cell size (AVG), percentage of hexagonal cell (HEX), and coefficient of variation (CV), central corneal thickness (CCT) were measured using a specular microscope. The Tear Break-Up Time (TUBT) and Schirmer tests were performed. Results: In Group 1 and Group 2, there was no significant difference between the smoker and the control groups in terms of CD, AVG, HEX and CV. In Group 3 and Group 4, there was a significant decrease in CD and HEX values, while there was a significant increase in AVG and CV values. CCT values were not significantly different in the Groups 1,2 and 3, whereas there was a significant decrease in the Group 4. TBUT and Schirmer tests were significantly decreased in all groups. Conclusion: It was found that as the number of pack-year increased, CD and HEX values decreased and AVG and CV values increased. Dry eye tests were affected in a shorter period of time, while CCT was affected in a longer period of time than the time required for CD, HEX, AVG and CV parameters to be affected.

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Annals of Medical Research

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Karakurt, Y., Sunar, M., Gamze Tasli, N., Ucak, T., Burcu Agcayazi, S., Ugurlu, A., & Icel, E. (2021). Evaluation of the effect of chronic smoking habit on corneal endothelial cells, central corneal thickness and dry eye tests . Annals of Medical Research