Evaluation of the effect of chronic smoking habit on corneal endothelial cells, central corneal thickness and dry eye tests

dc.contributor.authorKarakurt, Yucel
dc.contributor.authorSunar, Mukadder
dc.contributor.authorTasli, Nurdan Gamze
dc.contributor.authorUcak, Turgay
dc.contributor.authorAgcayazi, Sumeyye Burcu
dc.contributor.authorUgurlu, Adem
dc.contributor.authorIcel, Erel
dc.date.accessioned2022-03-01T10:44:07Z
dc.date.available2022-03-01T10:44:07Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: The aim of our study was to evaluate the effects of chronic smoking habit on corneal endothelial cells, central corneal thickness, and dry eye tests. Material and Methods: A total of 160 eyes of 160 chronic smokers and 160 eyes of 160 control cases were included in the study. The smokers were grouped into 4 groups according to pack-year smoking as follows: 0-10, 10-20, 20-30, >30. Endothelial cell density (CD), average cell size (AVG), percentage of hexagonal cell (HEX), and coefficient of variation (CV), central corneal thickness (CCT) were measured using a specular microscope. The Tear Break-Up Time (TUBT) and Schirmer tests were performed. Results: In Group 1 and Group 2, there was no significant difference between the smoker and the control groups in terms of CD, AVG, HEX and CV. In Group 3 and Group 4, there was a significant decrease in CD and HEX values, while there was a significant increase in AVG and CV values. CCT values were not significantly different in the Groups 1,2 and 3, whereas there was a significant decrease in the Group 4. TBUT and Schirmer tests were significantly decreased in all groups. Conclusion: It was found that as the number of pack-year increased, CD and HEX values decreased and AVG and CV values increased. Dry eye tests were affected in a shorter period of time, while CCT was affected in a longer period of time than the time required for CD, HEX, AVG and CV parameters to be affected.en_US
dc.identifier.citationKarakurt, Y., Sunar, M., Gamze Tasli, N., Ucak, T., Burcu Agcayazi, S., Ugurlu, A., & Icel, E. (2021). Evaluation of the effect of chronic smoking habit on corneal endothelial cells, central corneal thickness and dry eye tests . Annals of Medical Researchen_US
dc.identifier.urihttps://hdl.handle.net/11616/54074
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEvaluation of the effect of chronic smoking habit on corneal endothelial cells, central corneal thickness and dry eye testsen_US
dc.typeArticleen_US

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