Preparation of the L-Asparaginase-Based Biosensor With Polyimide Membrane Electrode for Monitoring L-Asparagine Levels in Leukemia

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dc.authoridAteş, Burhan/0000-0001-6080-229X
dc.authoridSEÇKİN, Turgay/0000-0001-8483-7366
dc.authoridYılmaz, İsmet/0000-0002-7204-1050
dc.authoridKoytepe, Suleyman/0000-0002-4788-278X
dc.authorwosidKöytepe, Süleyman/AAA-4168-2021
dc.authorwosidAteş, Burhan/AAA-3730-2021
dc.authorwosidSEÇKİN, Turgay/ABG-7537-2020
dc.authorwosidYılmaz, İsmet/P-9976-2015
dc.authorwosidYılmaz, ismet/AAG-8946-2019
dc.authorwosidERDOĞAN, Ali/ABG-8548-2020
dc.contributor.authorErdogan, Ali
dc.contributor.authorKoytepe, Suleyman
dc.contributor.authorAtes, Burhan
dc.contributor.authorYilmaz, Ismet
dc.contributor.authorSeckin, Turgay
dc.date.accessioned2024-08-04T20:39:45Z
dc.date.available2024-08-04T20:39:45Z
dc.date.issued2014
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPolyimide based amperometric biosensor was developed for the in vitro determination of L-asparagine in serum samples for monitoring L-asparagine levels in leukemia. First, polyimide from pyromellitic dianhydride and 4,4-oxydianiline (ODA) was prepared. This prepared polyimide was used as an immobilization membrane of L-asparaginase (L-ASNase) for L-ASNase-polyimide-coated electrodes. From the amperometric results for the polyimide electrode, it is concluded that polyimide membrane containing L-asparaginase can be used as a membrane for asparagine detection in the presence of large concentration of interferences, because of its strong adherence to the electrode surface, easy preparation, chemical stability, selectivity, and very high statistical confidence (R=0.9988).en_US
dc.identifier.doi10.1080/00914037.2014.886228
dc.identifier.endpage917en_US
dc.identifier.issn0091-4037
dc.identifier.issn1563-535X
dc.identifier.issue17en_US
dc.identifier.scopus2-s2.0-84903737703en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage909en_US
dc.identifier.urihttps://doi.org/10.1080/00914037.2014.886228
dc.identifier.urihttps://hdl.handle.net/11616/96491
dc.identifier.volume63en_US
dc.identifier.wosWOS:000338992100005en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Asen_US
dc.relation.ispartofInternational Journal of Polymeric Materials and Polymeric Biomaterialsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiosensoren_US
dc.subjectimmobilizationen_US
dc.subjectL-asparaginaseen_US
dc.subjectL-asparagineen_US
dc.subjectpolyimide membraneen_US
dc.titlePreparation of the L-Asparaginase-Based Biosensor With Polyimide Membrane Electrode for Monitoring L-Asparagine Levels in Leukemiaen_US
dc.typeArticleen_US

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