High-sensitivity electrochemical sensor using no nanomaterials for the detection of ciprofloxacin with poly 2-(hydroxymethyl)thiophene-modified glassy carbon electrode

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dc.authoridTitretir Duran, Serap/0000-0001-8361-9818
dc.authoridgungor, oznur/0000-0002-0664-1218
dc.contributor.authorBurc, Muammer
dc.contributor.authorGungor, Oznur
dc.contributor.authorDuran, Serap Titretir
dc.date.accessioned2024-08-04T20:54:41Z
dc.date.available2024-08-04T20:54:41Z
dc.date.issued2024
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this study, a new sensor was developed for the detection of ciprofloxacin that is easy to prepare, selective and has excellent sensitivity through electrochemical polymerization of 2-(hydroxymethyl)thiophene on glassy carbon (GC) electrode. Electrode modifications were performed by using cyclic voltammetry. The morphology and surface properties of the modified electrode were characterized by using scanning electron microscopy. Determination of ciprofloxacin with poly 2-(hydroxymethyl)thiophene-modified GC electrode was performed by square wave voltammetry in 0.1 M citrate buffer (pH 5.00) at 1.1 V. The prepared sensor showed a wide linear range from 0.1 to 200 mu M, detection limit of 7 nM, a limit of quantitation of 22 nM, a correlation coefficient of 0.9993, excellent sensitivity of 99.6% and a relative standard deviation of 0.40%. The sensor was used to determine ciprofloxacin in human urine samples, and a recovery efficiency of 99.24-100.36% was obtained. According to the results in this study, we believe that the sensor developed can be used for the detection of ciprofloxacin in clinical laboratories.en_US
dc.description.sponsorshipIdot;nn University Scientific Research Projects Coordination Uniten_US
dc.description.sponsorshipThis study was supported financially by & Idot;nonu University Scientific Research Projects Coordination Unit with the project numbered FYL-2018-1504. We thank Andrea Holck Karagozler for her help in editing the grammar and spelling errors of the manuscript.en_US
dc.identifier.doi10.1007/s00289-023-04995-z
dc.identifier.endpage6310en_US
dc.identifier.issn0170-0839
dc.identifier.issn1436-2449
dc.identifier.issue7en_US
dc.identifier.scopus2-s2.0-85171593114en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage6283en_US
dc.identifier.urihttps://doi.org/10.1007/s00289-023-04995-z
dc.identifier.urihttps://hdl.handle.net/11616/101576
dc.identifier.volume81en_US
dc.identifier.wosWOS:001068595200001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofPolymer Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCiprofloxacinen_US
dc.subjectElectrochemical sensoren_US
dc.subjectAntibioticen_US
dc.subject2-(Hydroxymethyl)thiophene polymeren_US
dc.subjectVoltammetryen_US
dc.titleHigh-sensitivity electrochemical sensor using no nanomaterials for the detection of ciprofloxacin with poly 2-(hydroxymethyl)thiophene-modified glassy carbon electrodeen_US
dc.typeArticleen_US

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