Implementation analyses of proteins and genes obtained from cancer patients
Küçük Resim Yok
Tarih
2016
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Tubitak Scientific & Technological Research Council Turkey
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Proteins are an important research area for scientists who are interested in bioinformatics and computational molecular biology, since these studies may result in important results in the case of diseases. Due to this, in this study, bioinformatics data were analyzed based on nucleotides and motifs. Bioinformatics data for proteins were obtained from two different databases. The obtained data belonged to cancer patients, and the genes in these DNA and protein sequences, the proteins synthesized by these sequences, and motifs in these data were analyzed. In the analysis, the ABCB1, ALOX5AP, AKT1, BRCA1, BRCA2, TNF, TNFSF13B, TP53, TP63, TP73, and WT1 genes were used. The proteins synthesized by genes belonging to similar classes were analyzed based on amino acid distributions, atomic distributions, Ramachandran plot similarities, and motifs.
Açıklama
Anahtar Kelimeler
Genes, proteins, cancer genes, motif discovery, Ramachandran diagrams
Kaynak
Turkish Journal of Electrical Engineering and Computer Sciences
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
24
Sayı
4
