Preemptive effectiveness of celecoxib in patients undergoing total abdominal hysterectomy

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dc.authorscopusid6506174296
dc.authorscopusid34569135700
dc.authorscopusid7003586739
dc.authorscopusid6603851680
dc.authorscopusid6701613323
dc.authorscopusid15073106000
dc.authorscopusid7004486274
dc.contributor.authorKaraaslan E.
dc.contributor.authorDurmuş M.
dc.contributor.authorDemirbilek S.
dc.contributor.authorKöro?lu A.
dc.contributor.authorTo?al T.
dc.contributor.authorKaraaslan K.
dc.contributor.authorErsoy M.O.
dc.date.accessioned2024-08-04T19:59:45Z
dc.date.available2024-08-04T19:59:45Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractWe aimed to investigate the effects of preemptive oral 100 mg and 200 mg celecoxib in relief of postoperative pain and morphine consumption after total abdominal hysterectomy. Fifty-four, ASA I-II class adult cases were enrolled in this study. One hour before the operation, celecoxib was administered per oral 100 and 200 mg to group I and II respectively and group III served as a control. All patients received IV PCA with morphine. PCA was programmed as follows: 2 mg loading dose, 1 mg bolus dose and 10 minutes lock-out time for a 20 mg limitation for four hours. All patients underwent a standardized general anaesthetic induction and maintenance. During the operation no analgesic medication was used. After operation, pain scores (VAS at rest, on movement and on coughing) were evaluated at 2, 4, 8, 12, 24, 48 and 72. hours. The morphine consumption was recorded at 2, 4, 8, 12 and 24. hours post-operatively. Sedation scores and peripheral oxygen saturation were recorded at 1, 2, 4, 8, 12, 16 and 24. hours post-operatively. The total morphine consumption was 24.78±5.95, 24.44±9.18 and 34.78±10.38 in group I, II and III. That consumption in group 3 was significantly higher than group I and II. VAS at rest, movement and coughing were significantly higher in group III. We concluded that preemptive oral celecoxib 100 mg may be used as an additive to IV PCA with morphine for post-operative analgesia after abdominal hysterectomy.en_US
dc.identifier.endpage88en_US
dc.identifier.issn1016-5150
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-0037304157en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage84en_US
dc.identifier.urihttps://hdl.handle.net/11616/90840
dc.identifier.volume31en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCelecoxiben_US
dc.subjectPatient controlled analgesia (PCA)en_US
dc.subjectPreemptive analgesiaen_US
dc.titlePreemptive effectiveness of celecoxib in patients undergoing total abdominal hysterectomyen_US
dc.title.alternativeTotal abdominal histerektomi olgularinda selekoksibin preemptif analjezik etkinli?ien_US
dc.typeArticleen_US

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