Immobilization of L-Asparaginase on Carrier Materials: A Comprehensive Review

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dc.authoridAteş, Burhan/0000-0001-6080-229X
dc.authoridUlu, Ahmet/0000-0002-4447-6233
dc.authorwosidAteş, Burhan/AAA-3730-2021
dc.authorwosidUlu, Ahmet/L-5180-2016
dc.contributor.authorUlu, Ahmet
dc.contributor.authorAtes, Burhan
dc.date.accessioned2024-08-04T20:43:13Z
dc.date.available2024-08-04T20:43:13Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThere are two major applications of L-asparaginase (L-ASNase): leukemia therapy and the food industry. Especially, its chemotherapeutic effect has attracted interest from the scientific community and individual scientists. Therefore, to protect the intrinsic activity and half-time of L-ASNase, several carriers and immobilization techniques for immobilization of L-ASNase have been described in articles. Unfortunately, a comprehensive review about immobilization of L-ASNase has not been written until now. In this review, we have thoroughly discussed the carriers for L-ASNase by illustrating immobilization findings including both past and present applications. In addition, we have revealed advantages and disadvantages of immobilized enzyme and related it to free form. We believe that this review will not only provide background information, but also guide future developments.en_US
dc.identifier.doi10.1021/acs.bioconjchem.7b00217
dc.identifier.endpage1610en_US
dc.identifier.issn1043-1802
dc.identifier.issn1520-4812
dc.identifier.issue6en_US
dc.identifier.pmid28505420en_US
dc.identifier.scopus2-s2.0-85021089003en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1598en_US
dc.identifier.urihttps://doi.org/10.1021/acs.bioconjchem.7b00217
dc.identifier.urihttps://hdl.handle.net/11616/97863
dc.identifier.volume28en_US
dc.identifier.wosWOS:000404090500002en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAmer Chemical Socen_US
dc.relation.ispartofBioconjugate Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLangmuir-Blodgett-Filmsen_US
dc.subjectConjugated L-Asparaginaseen_US
dc.subjectEnzyme L-Asparaginaseen_US
dc.subjectColi L-Asparaginaseen_US
dc.subjectPolyethylene-Glycolen_US
dc.subjectPeg-Asparaginaseen_US
dc.subjectNanoparticlesen_US
dc.subjectStabilizationen_US
dc.subjectChitosanen_US
dc.subjectTherapyen_US
dc.titleImmobilization of L-Asparaginase on Carrier Materials: A Comprehensive Reviewen_US
dc.typeReview Articleen_US

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