Outcomes of surgery for gallbladder cancer: A single-center experience
Küçük Resim Yok
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
OBJECTIVE: Gallbladder cancer (GBC) is a rare clinical entity that has a poor prognosis. Radical resection with meticulouslymph node dissection is the only treatment option. The aim of the present study is to evaluate the efficacy of radical resection for GBC in the early postoperative period with the viewpoint of clinicopathological correlation.METHODS: Patients (n=24) who underwent radical resection with lymph node dissection for GBC between 2015 and 2017were included. Demographic data, histopathologic tumor type, preoperative tumor markers, pathologic tumor size/stage(depth of invasion), lymph node metastasis and metastasis rates, and postoperative early mortality were evaluated. Thepatients were grouped in two groups according to lymph node metastases: Group 1 (without lymph node metastasis) andGroup 2 (with lymph node metastasis).RESULTS: The median age of the patients in Group 1 and Group 2 was 65 (range, 42–89) years and 68 (range, 48–87)years, respectively (p>0.05). The female/male ratio in Group 1 and Group 2 was 4/4 and 13/3, respectively (p>0.05). Therewas a tendency for increased metastasis in Group 2 compared with Group 1 (31% vs. 0%) (p>0.05). Also, 88% of the tumors in Group 2 were in the advanced stage, whereas the rate was 37% in Group 1 (p<0.05). There was early postoperativemortality in seven patients who underwent resection. Four of the seven patients (43%) were from Group 2 and three (37%)from Group 1 (p>0.05).CONCLUSION: Lymph node metastasis in GBC indicates advanced tumor stage. This causes a more complex surgical resection and therefore results in higher early postoperative mortality.
Açıklama
Anahtar Kelimeler
Kaynak
İstanbul Kuzey Klinikleri
WoS Q Değeri
Scopus Q Değeri
Cilt
5
Sayı
3
