Outcomes of surgery for gallbladder cancer: A single-center experience

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dc.contributor.authorBaşkıran, Adil
dc.contributor.authorŞahin, Emrah Kemal
dc.contributor.authorKaradağ, Neşe
dc.contributor.authorŞahin, Tevfik Tolga
dc.contributor.authorBarut, Bora
dc.contributor.authorÖzgor, Dinçer
dc.contributor.authorDirican, Abuzer
dc.date.accessioned2024-08-04T19:53:06Z
dc.date.available2024-08-04T19:53:06Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOBJECTIVE: Gallbladder cancer (GBC) is a rare clinical entity that has a poor prognosis. Radical resection with meticulouslymph node dissection is the only treatment option. The aim of the present study is to evaluate the efficacy of radical resection for GBC in the early postoperative period with the viewpoint of clinicopathological correlation.METHODS: Patients (n=24) who underwent radical resection with lymph node dissection for GBC between 2015 and 2017were included. Demographic data, histopathologic tumor type, preoperative tumor markers, pathologic tumor size/stage(depth of invasion), lymph node metastasis and metastasis rates, and postoperative early mortality were evaluated. Thepatients were grouped in two groups according to lymph node metastases: Group 1 (without lymph node metastasis) andGroup 2 (with lymph node metastasis).RESULTS: The median age of the patients in Group 1 and Group 2 was 65 (range, 42–89) years and 68 (range, 48–87)years, respectively (p>0.05). The female/male ratio in Group 1 and Group 2 was 4/4 and 13/3, respectively (p>0.05). Therewas a tendency for increased metastasis in Group 2 compared with Group 1 (31% vs. 0%) (p>0.05). Also, 88% of the tumors in Group 2 were in the advanced stage, whereas the rate was 37% in Group 1 (p<0.05). There was early postoperativemortality in seven patients who underwent resection. Four of the seven patients (43%) were from Group 2 and three (37%)from Group 1 (p>0.05).CONCLUSION: Lymph node metastasis in GBC indicates advanced tumor stage. This causes a more complex surgical resection and therefore results in higher early postoperative mortality.en_US
dc.identifier.doi10.14744/nci.2017.69320
dc.identifier.endpage198en_US
dc.identifier.issn2148-4902
dc.identifier.issn2536-4553
dc.identifier.issue3en_US
dc.identifier.startpage195en_US
dc.identifier.trdizinid372242en_US
dc.identifier.urihttps://doi.org/10.14744/nci.2017.69320
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/372242
dc.identifier.urihttps://hdl.handle.net/11616/89467
dc.identifier.volume5en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofİstanbul Kuzey Kliniklerien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleOutcomes of surgery for gallbladder cancer: A single-center experienceen_US
dc.typeArticleen_US

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