Effects of ketamine propofol mixture on intraocular pressure and hemodynamic in elderly patients a randomized double blind trial
Yükleniyor...
Dosyalar
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turkish Journal of Anesthesia and Reanimation
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: The aim of this study was to compare the effects of a ketamine-propofol mixture (ketofol) and propofol on intraocular pressure
(IOP) and haemodynamics in elderly patients during anaesthetic management at each repeated measurement times.
Methods: Forty elderly ASA I and II patients were divided into two random groups and received either propofol (1.5 mg kg-1; group
P, n=20) or ketofol (1:1 single syringe mixture of 5 mg mL-1 ketamine and 5 mg mL-1 propofol; group KP, n=20). A proseal laryngeal
mask airway (PLMA) was inserted 60 seconds after induction of anaesthesia. IOP, systolic blood pressure (SBP), diastolic blood pressure
(DBP), and heart rate (HR) values were recorded at preinduction (t0), immediately following induction (t1), and at 1 (t2), 3 (t3), and
5 (t4) minutes after induction. Haemodynamic complications and the need for ephedrine were also recorded.
Results: Patient characteristics at the beginning of the procedure were similar between the groups. SBP and HR were significantly increased
in group KP compared to group P at t1 and t4 (p=0.044). Induction of both anaesthetic agents significantly decreased the IOP
values from the t0 (p=0.026). A significant decrease in IOP was found at t1 and t4 in group P compared to group KP (p=0.018). The
total dose of ephedrine was statistically different in group P (p=0.034).
Conclusion: Ketofol can be an alternative agent to provide haemodynamic stability with a moderate decrease in IOP during anaesthesia
induction in elderly patients.
Açıklama
Anahtar Kelimeler
Intraocular pressure, Hemodynamic, Ketamine, Propofol, Elderly patient
Kaynak
Turkish Journal of Anesthesia and Reanimation
WoS Q Değeri
Scopus Q Değeri
Cilt
42
Sayı
Künye
Aydoğan, M. S. Demirel, S. Erdoğan, M. A. Fırat, P. Çolak, C. Durmuş, M. (2014). Effects of ketamine propofol mixture on intraocular pressure and hemodynamic in elderly patients a randomized double blind trial. Turkish Journal of Anesthesia and Reanimation. 42. 12-18.
