Female varicocele: A rat model
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Dosyalar
Tarih
1999
Dergi Başlığı
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Cilt Başlığı
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Abstract: Kadınlarda varikosel şu anda araştırma konusudur. Geliştirilecek bir hayvan modeli bu konuyla ilgili patolojileri ortaya koymak için uygun bir seçenek oluşturabilir. Bu amaçla virgin dişi Wistar raflarda ortahat laparatomi yapılarak sol renal ven bulunup çapı 0.85 mm olacak şekilde kısmi daraltma yapıldı. Bu darlık, metal bir prob ve renal ven etrafına konan 4-0 ipek bir sütür sonrası metal prob alınarak sağlandı. Makroskopik ve mikroskopik olarak modelimizi araştırdık. Sol ovarian vende ve intraovarian damarlarda belirgin dilatasyon gözlendi. Bu modelin kadın varikoseli patolojik değişikliklerini araştırmak için kolay ve ucuz bir yöntem olduğu sonucuna varıldı.
Abstract: Female varicocele is a subject of investigation. An animal model of female varicocele may be an option to detect pathologies associated with this phenomenon. For this purpose, a midline laparatomy was performed in female wistar rats. The left renal vein was identified and partially ligated to an external diameter of 0.85 mm. A consistent stenosis was achieved by using a 4-0 silk suture, which was ligated around both renal vein and a metal probe. The probe was removed and the vein was allowed to expand against the loop of suture. This model was macroscopically and microscopically investigated. Markedly dilated left ovarian vein and striking intraovarian venous congestion were observed. It was concluded that this model is an easy and cheap option to investigate female varicocele.
Abstract: Female varicocele is a subject of investigation. An animal model of female varicocele may be an option to detect pathologies associated with this phenomenon. For this purpose, a midline laparatomy was performed in female wistar rats. The left renal vein was identified and partially ligated to an external diameter of 0.85 mm. A consistent stenosis was achieved by using a 4-0 silk suture, which was ligated around both renal vein and a metal probe. The probe was removed and the vein was allowed to expand against the loop of suture. This model was macroscopically and microscopically investigated. Markedly dilated left ovarian vein and striking intraovarian venous congestion were observed. It was concluded that this model is an easy and cheap option to investigate female varicocele.
Açıklama
Anahtar Kelimeler
Kaynak
Turgut Özal Tıp Merkezi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
6
Sayı
3
Künye
GÖKDENİZ R,ÖZBEK E,MIZRAK B,ÖZEN S (1999). Female varicocele: A rat model. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, 6(3), 183 - 186.
