Acquired IgE-mediated food allergy after liver transplantation in children
dc.authorid | topal, erdem/0000-0002-4439-2689 | |
dc.authorid | BASKIRAN, ADIL/0000-0002-7536-1631 | |
dc.authorid | Varol, İlknur fatma/0000-0001-5212-218X | |
dc.authorwosid | topal, erdem/ABI-7545-2020 | |
dc.authorwosid | BASKIRAN, ADIL/ABI-2356-2020 | |
dc.authorwosid | Varol, İlknur fatma/ABH-6387-2020 | |
dc.contributor.author | Catal, F. | |
dc.contributor.author | Topal, E. | |
dc.contributor.author | Selimoglu, M. A. | |
dc.contributor.author | Karabiber, H. | |
dc.contributor.author | Baskiran, A. | |
dc.contributor.author | Senbaba, E. | |
dc.contributor.author | Varol, I. | |
dc.date.accessioned | 2024-08-04T20:40:21Z | |
dc.date.available | 2024-08-04T20:40:21Z | |
dc.date.issued | 2015 | |
dc.department | İnönü Üniversitesi | en_US |
dc.description.abstract | Background: In recent years, the number of studies regarding newly-diagnosed food allergies after liver transplantation has been increasing. In this study, we aimed to investigate the frequency, transplantation in children. Methods: Paediatric patients who underwent liver transplantation at Inonu University Faculty of Medicine, Organ Transplantation Institute were included in the study. Results: Forty-nine paediatric patients were enrolled in the study; 26 (53.1%) were female, the median age at transplantation was five years, and median follow-up time after transplantation was 16 months. Six patients (12.2%) developed IgE-mediated food allergies after transplantation; four had urticaria and/or angio-oedema and two developed anaphylaxis after food intake. Patients with and without IgE-mediated disease, immunosuppressant therapy with tacrolimus, and blood tacrolirnus level (p > 0.05 for each). Serum total IgE levels >= 100 IU/mL (p = 0.02) and peripheral eosinophilia (p = 0.026) were more common in the patients who developed IgE-mediated food allergies. In five of the six patients who developed IgE-mediated food allergies, reaction occurred within the first year after transplantation; the risk of developing a reaction was 2.7 times higher within the first year after transplantation than in subsequent years (95% CI, 1.546-4.914; p=0.026). No Epstein-Barr virus or cytomegalovirus infections were detected in any of the patients who developed IgE-mediated food allergies after liver transplantation. Conclusion: The risk of developing IgE-mediated food allergies is approximately three times higher within the first year after transplantation than in subsequent years. (C) 2014 SEICAP Published by Elsevier Espana, S.L.U. All rights reserved. | en_US |
dc.identifier.doi | 10.1016/j.aller.2014.05.003 | |
dc.identifier.endpage | 397 | en_US |
dc.identifier.issn | 0301-0546 | |
dc.identifier.issn | 1578-1267 | |
dc.identifier.issue | 4 | en_US |
dc.identifier.pmid | 25201761 | en_US |
dc.identifier.scopus | 2-s2.0-84937633438 | en_US |
dc.identifier.scopusquality | Q3 | en_US |
dc.identifier.startpage | 392 | en_US |
dc.identifier.uri | https://doi.org/10.1016/j.aller.2014.05.003 | |
dc.identifier.uri | https://hdl.handle.net/11616/96876 | |
dc.identifier.volume | 43 | en_US |
dc.identifier.wos | WOS:000357842600009 | en_US |
dc.identifier.wosquality | Q4 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier Espana Slu | en_US |
dc.relation.ispartof | Allergologia Et Immunopathologia | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Children | en_US |
dc.subject | Food | en_US |
dc.subject | Allergy | en_US |
dc.subject | Liver | en_US |
dc.subject | Transplantation | en_US |
dc.subject | IgE-mediated | en_US |
dc.subject | Tacrolimus | en_US |
dc.title | Acquired IgE-mediated food allergy after liver transplantation in children | en_US |
dc.type | Article | en_US |