Effects of Hexachlorocyclohexane (HCH-?-Isomer, Lindane) on the Reproductive System of Zebrafish (Danio rerio)
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Central Fisheries Research Inst
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
In this study, histopathological changes induced by lindane a gamma isomer of hexachlorocyclohexane and its intoxication associated with reproductive system and hormone levels were investigated in zebrafish. In all, 320 zebrafish adults approximately 1 year in age, (Danio rerio) obtained from a commercial entity were used in the study. Zebrafish were divided into 8 groups, each one containing 40 zebrafish. Groups were organized as 0 (the control group), 1 ml/L methanol, and 5, 10, 20, 40, 80, 160 mu g/L/day lindane. In the study, the gamma-HCH-isomer was applied at rates of 5/10/20/40/80/160 mu g/L/day as doses of immersion to each group for 21 days. Macroscopically, the drop in egg production was observed, especially in the 80 and 160 mu g/L/day groups of female zebrafish. A microscopic decrease in ovulation and biochemical decreases in estradiol (E-2) levels (40/80/160 mu g/L) were also observed in the female zebrafish. As a result, lindane was found to cause changes in the reproductive system, and consequently, to cause hormonal disorders and to have significant effects on ovulation and fertilization in the female zebrafish.
Açıklama
Anahtar Kelimeler
Zebrafish, ovulation, fertilization, histopathology
Kaynak
Turkish Journal of Fisheries and Aquatic Sciences
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
16
Sayı
4
