Determination of allergen-specific IgE in patients with atopy or allergy symptoms
Küçük Resim Yok
Tarih
2003
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
OBJECTIVES: We investigated the role of specific IgE assay in the diagnosis in patients found to be atopic or allergic by history and physical examination. PATIENTS AND METHODS: Serum specific IgE levels were measured by the chemiluminescent assay in 143 adults (58 females, 85 males; mean age 34.3 years; range 16 to 62 years) and in 113 children (62 girls, 51 boys; mean age 10.2 years; range 5 to 16 years) with rhinitis, asthma, or dermatitis. The results were analyzed in six groups depending on the specific IgE level (no specific IgE, very low, low, moderate, high, and very high levels). The specific IgE threshold for a negative or positive result was accepted as 0.70 IU/ml. Allergen-specific IgE antibodies were sought for 35 allergens in adults, and for 19 allergens in children. RESULTS: Specific IgE levels were positive (>0.70 IU/ml) in 92 adults (64.34%) and in 50 children (44.25%). Hypersensitivity to individual allergens ranged between 20.08% and 41.96% in adults, and between 17.70% and 28.32% in children. Fourteen adults and eight children showed sensitivity to a single allergen; the remaining patients were sensitive to at least two allergens. CONCLUSION: Detection of sensitivity to allergens is complementary to findings obtained by history and physical examination and may help to reveal allergic etiology in patients presenting with a similar symptom profile.
Açıklama
Anahtar Kelimeler
immunoglobulin E, adolescent, adult, article, asthma, atopic dermatitis, blood, chemoluminescence, child, female, human, immunology, male, middle aged, perennial rhinitis, preschool child, Adolescent, Adult, Asthma, Chemiluminescent Measurements, Child, Child, Preschool, Dermatitis, Atopic, Female, Humans, Immunoglobulin E, Male, Middle Aged, Rhinitis, Allergic, Perennial
Kaynak
Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
10
Sayı
5
