Determination of allergen-specific IgE in patients with atopy or allergy symptoms

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dc.authorscopusid6603959009
dc.authorscopusid6603062857
dc.authorscopusid7003373872
dc.authorscopusid7007027214
dc.contributor.authorMiman M.C.
dc.contributor.authorOzerol I.H.
dc.contributor.authorOzturan O.
dc.contributor.authorErdem T.
dc.date.accessioned2024-08-04T20:01:07Z
dc.date.available2024-08-04T20:01:07Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOBJECTIVES: We investigated the role of specific IgE assay in the diagnosis in patients found to be atopic or allergic by history and physical examination. PATIENTS AND METHODS: Serum specific IgE levels were measured by the chemiluminescent assay in 143 adults (58 females, 85 males; mean age 34.3 years; range 16 to 62 years) and in 113 children (62 girls, 51 boys; mean age 10.2 years; range 5 to 16 years) with rhinitis, asthma, or dermatitis. The results were analyzed in six groups depending on the specific IgE level (no specific IgE, very low, low, moderate, high, and very high levels). The specific IgE threshold for a negative or positive result was accepted as 0.70 IU/ml. Allergen-specific IgE antibodies were sought for 35 allergens in adults, and for 19 allergens in children. RESULTS: Specific IgE levels were positive (>0.70 IU/ml) in 92 adults (64.34%) and in 50 children (44.25%). Hypersensitivity to individual allergens ranged between 20.08% and 41.96% in adults, and between 17.70% and 28.32% in children. Fourteen adults and eight children showed sensitivity to a single allergen; the remaining patients were sensitive to at least two allergens. CONCLUSION: Detection of sensitivity to allergens is complementary to findings obtained by history and physical examination and may help to reveal allergic etiology in patients presenting with a similar symptom profile.en_US
dc.identifier.endpage193en_US
dc.identifier.issn1300-7475
dc.identifier.issue5en_US
dc.identifier.pmid12970591en_US
dc.identifier.scopus2-s2.0-0642280805en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage188en_US
dc.identifier.urihttps://hdl.handle.net/11616/91272
dc.identifier.volume10en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.relation.ispartofKulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throaten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectimmunoglobulin Een_US
dc.subjectadolescenten_US
dc.subjectadulten_US
dc.subjectarticleen_US
dc.subjectasthmaen_US
dc.subjectatopic dermatitisen_US
dc.subjectblooden_US
dc.subjectchemoluminescenceen_US
dc.subjectchilden_US
dc.subjectfemaleen_US
dc.subjecthumanen_US
dc.subjectimmunologyen_US
dc.subjectmaleen_US
dc.subjectmiddle ageden_US
dc.subjectperennial rhinitisen_US
dc.subjectpreschool childen_US
dc.subjectAdolescenten_US
dc.subjectAdulten_US
dc.subjectAsthmaen_US
dc.subjectChemiluminescent Measurementsen_US
dc.subjectChilden_US
dc.subjectChild, Preschoolen_US
dc.subjectDermatitis, Atopicen_US
dc.subjectFemaleen_US
dc.subjectHumansen_US
dc.subjectImmunoglobulin Een_US
dc.subjectMaleen_US
dc.subjectMiddle Ageden_US
dc.subjectRhinitis, Allergic, Perennialen_US
dc.titleDetermination of allergen-specific IgE in patients with atopy or allergy symptomsen_US
dc.title.alternativeAtopi veya alerjili olgularda alerjen-spesifik IgE düzeyleri.en_US
dc.typeArticleen_US

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