Surgical excision, cryotherapy, autolimbal transplantation and mitomycin-C in treatment of conjunctival-corneal intraepithelial neoplasia.
Küçük Resim Yok
Tarih
2005
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
PURPOSE: To report surgical excision, cryotherapy, autologous conjunctival-limbal transplantation and topical mitomycin C (MMC) in the patient with extensive conjunctival-corneal intraepithelial neoplasia. METHODS: Case report and literature review. RESULTS: A 75-year-old woman was referred to our department with the diagnosis of conjunctival-corneal neoplasia. Slit-lamp microscopic examination revealed an extensive papilliform tumoral mass invading the limbus at 360-degrees, and bulbar conjunctiva and cornea. Visual acuity was finger counting from 2 m in the right eye and 20/20 in the left eye. We performed total surgical excision, cryotherapy and autologous conjunctival-limbal transplantation in the right eye. Mitomycin-C 0.02% eye drops four times a day were prescribed for 4 weeks after the surgery. After the treatment, the visual acuity increased to 0.7 in the right eye. Corneal epithelium completely healed within 1 week after the surgery. No corneal epithelium-related problem or neoplasia recurrence were noted during the 2-year follow-up period. CONCLUSIONS: This technique may be useful in reconstruction of eyes with extensive neoplastic involvement of the conjunctiva, limbus, and cornea. In addition, mitomycin C drops may be useful in preventing postoperative recurrence of conjunctival-corneal intraepithelial neoplasia.
Açıklama
Anahtar Kelimeler
antineoplastic antibiotic, mitomycin, aged, article, autotransplantation, carcinoma in situ, case report, conjunctiva tumor, cornea disease, cornea epithelium, cornea limbus, cornea transplantation, cryotherapy, female, follow up, human, methodology, pathology, Aged, Antibiotics, Antineoplastic, Carcinoma in Situ, Conjunctival Neoplasms, Corneal Diseases, Corneal Transplantation, Cryotherapy, Epithelium, Corneal, Female, Follow-Up Studies, Humans, Limbus Corneae, Mitomycin, Transplantation, Autologous, MLCS, MLOWN
Kaynak
International ophthalmology
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
26
Sayı
1-2
