Surgical excision, cryotherapy, autolimbal transplantation and mitomycin-C in treatment of conjunctival-corneal intraepithelial neoplasia.

Basit Öğe Kaydı
dc.authorscopusid6701346723
dc.authorscopusid20133975300
dc.authorscopusid15056850500
dc.authorscopusid6508081411
dc.contributor.authorDoganay S.
dc.contributor.authorEr H.
dc.contributor.authorTasar A.
dc.contributor.authorGürses I.
dc.date.accessioned2024-08-04T19:59:16Z
dc.date.available2024-08-04T19:59:16Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPURPOSE: To report surgical excision, cryotherapy, autologous conjunctival-limbal transplantation and topical mitomycin C (MMC) in the patient with extensive conjunctival-corneal intraepithelial neoplasia. METHODS: Case report and literature review. RESULTS: A 75-year-old woman was referred to our department with the diagnosis of conjunctival-corneal neoplasia. Slit-lamp microscopic examination revealed an extensive papilliform tumoral mass invading the limbus at 360-degrees, and bulbar conjunctiva and cornea. Visual acuity was finger counting from 2 m in the right eye and 20/20 in the left eye. We performed total surgical excision, cryotherapy and autologous conjunctival-limbal transplantation in the right eye. Mitomycin-C 0.02% eye drops four times a day were prescribed for 4 weeks after the surgery. After the treatment, the visual acuity increased to 0.7 in the right eye. Corneal epithelium completely healed within 1 week after the surgery. No corneal epithelium-related problem or neoplasia recurrence were noted during the 2-year follow-up period. CONCLUSIONS: This technique may be useful in reconstruction of eyes with extensive neoplastic involvement of the conjunctiva, limbus, and cornea. In addition, mitomycin C drops may be useful in preventing postoperative recurrence of conjunctival-corneal intraepithelial neoplasia.en_US
dc.identifier.doi10.1007/s10792-006-0006-6
dc.identifier.endpage57en_US
dc.identifier.issn0165-5701
dc.identifier.issue1-2en_US
dc.identifier.pmid16779567en_US
dc.identifier.scopus2-s2.0-33750741998en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage53en_US
dc.identifier.urihttps://doi.org/10.1007/s10792-006-0006-6
dc.identifier.urihttps://hdl.handle.net/11616/90517
dc.identifier.volume26en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofInternational ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectantineoplastic antibioticen_US
dc.subjectmitomycinen_US
dc.subjectageden_US
dc.subjectarticleen_US
dc.subjectautotransplantationen_US
dc.subjectcarcinoma in situen_US
dc.subjectcase reporten_US
dc.subjectconjunctiva tumoren_US
dc.subjectcornea diseaseen_US
dc.subjectcornea epitheliumen_US
dc.subjectcornea limbusen_US
dc.subjectcornea transplantationen_US
dc.subjectcryotherapyen_US
dc.subjectfemaleen_US
dc.subjectfollow upen_US
dc.subjecthumanen_US
dc.subjectmethodologyen_US
dc.subjectpathologyen_US
dc.subjectAgeden_US
dc.subjectAntibiotics, Antineoplasticen_US
dc.subjectCarcinoma in Situen_US
dc.subjectConjunctival Neoplasmsen_US
dc.subjectCorneal Diseasesen_US
dc.subjectCorneal Transplantationen_US
dc.subjectCryotherapyen_US
dc.subjectEpithelium, Cornealen_US
dc.subjectFemaleen_US
dc.subjectFollow-Up Studiesen_US
dc.subjectHumansen_US
dc.subjectLimbus Corneaeen_US
dc.subjectMitomycinen_US
dc.subjectTransplantation, Autologousen_US
dc.subjectMLCSen_US
dc.subjectMLOWNen_US
dc.titleSurgical excision, cryotherapy, autolimbal transplantation and mitomycin-C in treatment of conjunctival-corneal intraepithelial neoplasia.en_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu