Learning of serial digits leads to frontal activation in functional MR imaging
Küçük Resim Yok
Tarih
2006
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose: Clinical studies have shown that performance on the serial digit learning test (SDLT) is dependent upon the mesial temporal lobes, which are responsible for learning and its consolidation. However, an effective SDLT performance is also dependent upon sequencing, temporal ordering, and the utilization of mnemonic strategies. All of these processes are among the functions of the frontal lobes, in spite of this, the relationship between SDLT performance and the frontal lobes has not been demonstrated with previously used mapping techniques. The aim of this study was to investigate the areas of the brain that are activated by SDLT performance. Materials and methods: Ten healthy, eight handed volunteers (mean age, 20.1 years; SD: 3.3) who had 12 years of education were studied with a 1.0 T MR imaging scanner. BOLD (blood oxygen level dependent) contrast and a modified SDLT were used. Activated loci were automatically mapped using a proportional grid. Results: In learning, the most consistent activation was observed in B-a-7 of the right (80%) and the left hemispheres (50%). In recall, the most consistent activation was observed in B-a-7 of the eight hemisphere (60%). Activations were observed in 2.5±0.97 Talairach volumes in learning, whereas they encompassed 1.7±0.95 volumes in recall. The difference between both phases (learning and recall) regarding total activated volume was significant (p<0.05). Conclusion: The prefrontal activation during SDLT performance was not related to learning or to recall, but to a function that is common to both of these cognitive processes. A candidate for this common factor may be the executive functions, which also include serial position processing and temporal ordering. © Turkish Society of Radiology 2006.
Açıklama
Anahtar Kelimeler
Frontal lobe, Functional magnetic resonance imaging, Prefrontal area, Sequencing, Serial digit learning test, Temporal ordering
Kaynak
Diagnostic and Interventional Radiology
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
12
Sayı
1
