The significance of MPV and N/L value in diagnosis of endometrial cancer

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dc.authorscopusid55274353300
dc.authorscopusid8423926300
dc.authorscopusid56720163300
dc.authorscopusid6505910645
dc.authorscopusid57190815030
dc.authorscopusid6603256061
dc.contributor.authorYılmaz E.
dc.contributor.authorCoşkun E.İ.
dc.contributor.authorŞahin N.
dc.contributor.authorElkıran T.
dc.contributor.authorÇıplak B.
dc.contributor.authorŞimşek Y.
dc.date.accessioned2024-08-04T20:01:13Z
dc.date.available2024-08-04T20:01:13Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: Endometrial cancer is the most often determined malignancy. Beyond the factors like unopposed estrogen, endometrial hyperplasia, the existence of chronic inflammation has been thaugt as responsible also for the ethiology of endometrial cancer as in all tumours. In this study we tried to find out the role of chronic inflammation in endometrium cancer by using the hemaetologic markers like MPV, N/L. Material and Method: There has been 111 patients included in the study. Patients are diveded into four groups according to the endometrial tissue sampling results. Endometrial samplings are diagnosed in the pathology laboratory by their histopathologic characteristics. Total blood count is done by using Siemens Healthcare Diagnostic Item ADVIA 2120i. For the statistical analysis, SPSS 22.0, Chicago, IL programme has been used. Results: In the statistical analysis, there is not a significant difference of N/L ratios between groups (P>0.05). As the MPV values are examined, there has been significant difference between groups and in the endometrial cancer group, this value has been higher (p<0.001). Discussion: Chronic inflammation is an important factor in the ethiology of carcinogenesis. It has been showed that the cells causing inflammation; lymphocytes, platelets and especially neutrophils are increased in the tumoral tissue and their metabolisms are also increased in the tumoral tissue. It is not so different in gynecologic cancers like our study. In this case agents slowing down the inflammatory process, render an important part of the cancer therapy. © 2017 Gunes Kitap Kirtasiye. All rights reserved.en_US
dc.identifier.endpage36en_US
dc.identifier.issn1301-8841
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85026866420en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage33en_US
dc.identifier.urihttps://hdl.handle.net/11616/91338
dc.identifier.volume19en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherGunes Kitap Kirtasiyeen_US
dc.relation.ispartofTurk Jinekolojik Onkoloji Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEndometrial Canceren_US
dc.subjectMPVen_US
dc.subjectN/Len_US
dc.subjectİnflamationen_US
dc.titleThe significance of MPV and N/L value in diagnosis of endometrial canceren_US
dc.title.alternativeEndometrium kanserininin teşhisinde MPV ve N/L değerlerinin Önemien_US
dc.typeArticleen_US

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