Determination of 3,4-dihydroxyphenylacetic acid in the presence of ascorbic acid and uric acid at poly(p-aminobenzene sulfonic acid) conducting polymer electrode
Küçük Resim Yok
Tarih
2017
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Poly(p-aminobenzene sulfonic acid) [poly(p-ABSA)] modified glassy carbon electrode (GCE) was used for the simultaneous determination of ascorbic acid (AA), 3,4-dihydroxyphenylacetic acid (DOPAC) and uric acid (UA). The polymer film was grown on GCE by the cyclic voltammetry method in the potential range from -1.5 to +2.5 V at a scan rate of 50 mV s(-1) for 14 cycles in 0.1 M KCl solution containing 5 mM p-ABSA. The anodic peaks for AA, DOPAC and UA at the poly(p-ABSA)/GCE were resolved in phosphate buffer solution (pH 7.0). On the other hand, the electro-oxidation peak current of AA, DOPAC and UA showed linear dynamic range, good stability and sensitivity. The linear range of DOPAC is over four orders of magnitude (R (2) = 0.998). The detection limit of DOPAC is 2.96 x 10(-7) mol L-1. The proposed method and electrode have been successfully applied for the determination of DOPAC in urine and blood serum samples and pharmaceutical tablets, demonstrating the stability and reliability of the proposed method and electrode.
Açıklama
Anahtar Kelimeler
3,4-Dihydroxyphenylacetic acid, Poly(p-aminobenzene sulfonic acid), Conducting polymer electrode, Ascorbic acid, Uric acid
Kaynak
Polymer Bulletin
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
74
Sayı
10
