Determination of 3,4-dihydroxyphenylacetic acid in the presence of ascorbic acid and uric acid at poly(p-aminobenzene sulfonic acid) conducting polymer electrode

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dc.authoridERDOGDU, GAMZE/0000-0002-8114-6946
dc.authoridKuyumcu Savan, Ebru/0000-0002-8851-0907
dc.authorwosidERDOGDU, GAMZE/ABG-7776-2020
dc.authorwosidKuyumcu Savan, Ebru/E-3430-2019
dc.contributor.authorSavan, Ebru Kuyumcu
dc.contributor.authorErdogdu, Gamze
dc.date.accessioned2024-08-04T20:43:00Z
dc.date.available2024-08-04T20:43:00Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPoly(p-aminobenzene sulfonic acid) [poly(p-ABSA)] modified glassy carbon electrode (GCE) was used for the simultaneous determination of ascorbic acid (AA), 3,4-dihydroxyphenylacetic acid (DOPAC) and uric acid (UA). The polymer film was grown on GCE by the cyclic voltammetry method in the potential range from -1.5 to +2.5 V at a scan rate of 50 mV s(-1) for 14 cycles in 0.1 M KCl solution containing 5 mM p-ABSA. The anodic peaks for AA, DOPAC and UA at the poly(p-ABSA)/GCE were resolved in phosphate buffer solution (pH 7.0). On the other hand, the electro-oxidation peak current of AA, DOPAC and UA showed linear dynamic range, good stability and sensitivity. The linear range of DOPAC is over four orders of magnitude (R (2) = 0.998). The detection limit of DOPAC is 2.96 x 10(-7) mol L-1. The proposed method and electrode have been successfully applied for the determination of DOPAC in urine and blood serum samples and pharmaceutical tablets, demonstrating the stability and reliability of the proposed method and electrode.en_US
dc.description.sponsorshipResearch Fund Unit of Inonu University [APYB: 2011/38]en_US
dc.description.sponsorshipThis study was financially supported by the Research Fund Unit of Inonu University (Grant No. APYB: 2011/38).en_US
dc.identifier.doi10.1007/s00289-017-1957-7
dc.identifier.endpage4360en_US
dc.identifier.issn0170-0839
dc.identifier.issn1436-2449
dc.identifier.issue10en_US
dc.identifier.scopus2-s2.0-85014033496en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage4349en_US
dc.identifier.urihttps://doi.org/10.1007/s00289-017-1957-7
dc.identifier.urihttps://hdl.handle.net/11616/97711
dc.identifier.volume74en_US
dc.identifier.wosWOS:000408004200027en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofPolymer Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject3,4-Dihydroxyphenylacetic aciden_US
dc.subjectPoly(p-aminobenzene sulfonic acid)en_US
dc.subjectConducting polymer electrodeen_US
dc.subjectAscorbic aciden_US
dc.subjectUric aciden_US
dc.titleDetermination of 3,4-dihydroxyphenylacetic acid in the presence of ascorbic acid and uric acid at poly(p-aminobenzene sulfonic acid) conducting polymer electrodeen_US
dc.typeArticleen_US

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