Daptomycin in combination with rosuvastatin induced blood creatine phosphokinase elevation

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dc.authoridDurmus, Mefkure/0000-0001-9745-4196
dc.authoridBahçecioğlu, Ömer Faruk/0000-0002-4045-4555
dc.authorwosidDurmus, Mefkure/ISR-9328-2023
dc.authorwosidBahçecioğlu, Ömer Faruk/AAA-7477-2021
dc.contributor.authorDurmus, Mefkure
dc.contributor.authorBahcecioglu, Omer Faruk
dc.contributor.authorGok, Selim
dc.date.accessioned2024-08-04T20:47:12Z
dc.date.available2024-08-04T20:47:12Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractWe present the case of a 73-year-old male patient who was hospitalised with infective endocarditis, and report an elevation in his blood creatine phosphokinase (CPK) after receiving daptomycin and rosuvastatin therapy concomitantly. His previous home-scheduled medications included apixaban, ivabradine, metformin, rosuvastatin 20 mg, ginkgo biloba and trimetazidine, and he continued to receive these medications at the hospital. After three sets of blood cultures were taken, empirical treatment was started with vancomycin and gentamicin. On the eighth day of treatment, daptomycin and ampicillin-sulbactam were initiated due to ampicillin-resistant Enterococcus faecalis growth in the patient's blood culture. Daptomycin and rosuvastatin were discontinued on the 23rd day of treatment because of blood CPK elevation (2416 U/L) and linezolid was started instead of daptomycin. Six days after discontinuation of daptomycin and rosuvastatin, the CPK concentrations returned to normal range.en_US
dc.identifier.doi10.1136/ejhpharm-2020-002218
dc.identifier.endpage236en_US
dc.identifier.issn2047-9956
dc.identifier.issn2047-9964
dc.identifier.issue4en_US
dc.identifier.pmid34162676en_US
dc.identifier.scopus2-s2.0-85081535811en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage234en_US
dc.identifier.urihttps://doi.org/10.1136/ejhpharm-2020-002218
dc.identifier.urihttps://hdl.handle.net/11616/99220
dc.identifier.volume28en_US
dc.identifier.wosWOS:000667716700012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBmj Publishing Groupen_US
dc.relation.ispartofEuropean Journal of Hospital Pharmacyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectclinical pharmacyen_US
dc.subjectcardiologyen_US
dc.subjectinfection controlen_US
dc.subjectside effects of drugsen_US
dc.subjectcase reporten_US
dc.titleDaptomycin in combination with rosuvastatin induced blood creatine phosphokinase elevationen_US
dc.typeArticleen_US

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