An investigation into the factors predicting acute appendicitis and perforated appendicitis

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dc.contributor.authorAkbulut, Sami
dc.contributor.authorKoç, Cemalettin
dc.contributor.authorŞahin, Tevfik Tolga
dc.contributor.authorŞahin, Emre
dc.contributor.authorTuncer, Adem
dc.contributor.authorDemyati, Khaled
dc.contributor.authorŞamdancı, Emine Türkmen
dc.contributor.authorÇolak, Cemil
dc.contributor.authorYılmaz, Sezai
dc.date.accessioned2022-12-09T10:46:04Z
dc.date.available2022-12-09T10:46:04Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBACKGROUND: To investigate the factors predicting acute appendicitis (AAp) and perforated AAp in patients who underwent surgery with a preliminary diagnosis of AAp. METHODS: Between May 2009 and December 2018, 1316 patients underwent appendectomy with a presumed diagnosis of AAp. To investigate the factors predicting AAp, patients were divided into two groups considering the histopathological presence of inflammatory changes in the appendix: AAp positive (AAp group; n=1043) and AAp negative (Non-AAp group; n=273). Also, to investigate the factors predicting appendiceal perforation, patients with AAp were divided into two groups considering the presence of perforation: non-perforated AAp (n=850) and perforated AAp (n=193). ROC curve analysis was used to identify optimum cut-off values of quantitative variables. The groups were compared using univariate analysis methods and parameters with a p? 0.20 were taken into a multivariate logistic regression model. RESULTS: Multivariate analysis method related to factors predicting AAp showed that gender (male; p=0.034; OR=1.4), WBC (?10.900; p=0.022; OR=1.5), MPV (?29.1; p=0.006; OR=1.6), TBil (?0.61; p=0.034; OR=1.4), CRP (?0.725; p=0.002; OR=1.7), NLR (?5.13; p=0.034; OR=1.5), PNR (<24.04; p=0.001; OR=1.9) and US findings (AAp+; p<0.001; OR=2.9) were independent factors for predicting AAp. Multivariate analysis method related to factors predicting appendiceal perforation showed that age (?32 years; p<0.001; OR=2.5), TBil (?0.67; p=0.046; OR=1.5), CRP (?3.75; p<0.001; OR=3.0) and NLR (?5.69; p=0.006; OR=1.8) were independent factors for predicting perforated AAp. CONCLUSION: We believe that predicting both AAp and perforation will help the clinician evaluate patients who applied to the emergency unit with presumed diagnosis AAp. This approach will also contribute to reducing the negative appendectomy and perforation rates.en_US
dc.identifier.citationAKBULUT A, KOÇ C, ŞAHİN T, ŞAHİN E, TUNCER A, DEMYATİ K, ŞAMDANCI E, ÇOLAK C, YILMAZ S (2021). An investigation into the factors predicting acute appendicitis and perforated appendicitis. Ulusal Travma ve Acil Cerrahi Dergisi, 27(4), 434 - 442. 10.14744/tjtes.2020.60344en_US
dc.identifier.doi10.14744/tjtes.2020.60344en_US
dc.identifier.endpage442en_US
dc.identifier.issn1306-696X
dc.identifier.issn1307-7945
dc.identifier.issue4en_US
dc.identifier.pmid34213000en_US
dc.identifier.scopus2-s2.0-85110381514en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage434en_US
dc.identifier.trdizinid505931en_US
dc.identifier.urihttps://doi.org/10.14744/tjtes.2020.60344
dc.identifier.urihttps://hdl.handle.net/11616/85666
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/505931
dc.identifier.volume27en_US
dc.identifier.wosWOS:000669548700008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofUlusal Travma ve Acil Cerrahi Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleAn investigation into the factors predicting acute appendicitis and perforated appendicitisen_US
dc.typeArticleen_US

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